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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E5RGR0 LYPLA1 Acyl-protein thioesterase 1 (EC 3.1.2.22) … Homo sapiens (Human) 197 aa

Protein Details: E5RGR0 (LYPLA1)

Protein Information
Accession E5RGR0
Protein Names Acyl-protein thioesterase 1 (EC 3.1.2.22) (Lysophospholipase 1) (Lysophospholipase I) (Palmitoyl-protein hydrolase)
Gene Symbol LYPLA1
Organism Homo sapiens (Human)
Length 197 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.923
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.923
24/46 (52.2%)
2
DU145 cells
Specificity: 0.077
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MCGNNMSTPL11PAIVPAARKA21TAAVIFLHGL31GDTGHGWAEA41FAGIRSSHIK
51-10051YICPHAFDII61GLSPDSQEDE71SGIKQAAENI81KALIDQEVKN91GIPSNRIILG
101-150101GFSQGGALSL111YTALTTQQKL121AGVTALSCWL131PLRASFPQGP141IGGANRDISI
151-197151LQCHGDCDPL161VPLMFGSLTV171EKLKTLVNPA181NVTFKTYEGM191MHSSCQQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
2 Prediction (High) - -
128 CYSMODDB SWISSPALM DBPTM Prediction (High) Phospholipase/Carboxylesterase -
195 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons