Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E5RGR0 | LYPLA1 | Acyl-protein thioesterase 1 (EC 3.1.2.22) … | Homo sapiens (Human) | 197 aa |
Protein Details: E5RGR0 (LYPLA1)
Protein Information
| Accession | E5RGR0 |
|---|---|
| Protein Names | Acyl-protein thioesterase 1 (EC 3.1.2.22) (Lysophospholipase 1) (Lysophospholipase I) (Palmitoyl-protein hydrolase) |
| Gene Symbol | LYPLA1 |
| Organism | Homo sapiens (Human) |
| Length | 197 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MCGNNMSTPL11PAIVPAARKA21TAAVIFLHGL31GDTGHGWAEA41FAGIRSSHIK
51-10051YICPHAFDII61GLSPDSQEDE71SGIKQAAENI81KALIDQEVKN91GIPSNRIILG
101-150101GFSQGGALSL111YTALTTQQKL121AGVTALSCWL131PLRASFPQGP141IGGANRDISI
151-197151LQCHGDCDPL161VPLMFGSLTV171EKLKTLVNPA181NVTFKTYEGM191MHSSCQQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 2 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.03
|
|
| 53 | - | - | - |
Deep-Palm: 0.80
|
|
| 128 | SWISSPALM DBPTM CYSMODDB | Phospholipase/Carboxylesterase |
HeLa
(29575903)
|
Unknown
(32651440)
|
GPS-Palm: 0.94
Deep-Palm: 0.97
|
| 153 | - | - | - |
Deep-Palm: 0.82
|
|
| 157 | - | - | - |
Deep-Palm: 0.79
|
|
| 195 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.01
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.