Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E5RIU8 | ANXA6 | Annexin A6 | Homo sapiens (Human) | 95 aa |
Protein Details: E5RIU8 (ANXA6)
Protein Information
| Accession | E5RIU8 |
|---|---|
| Protein Names | Annexin A6 |
| Gene Symbol | ANXA6 |
| Organism | Homo sapiens (Human) |
| Length | 95 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAKPAQGAKY11RGSIHDFPGF21DPNQDAEALY31TAMKGFGSDK41EAILDIITSR
51-9551SNRQRQEVCQ61SYKSLYGKDL71IADLKYELTG81KFERLIVGGL91SDVGT
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 59 | - | - | - |
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.444
4/4 (100.0%)
3
cerebral cortex
Specificity: 0.333
3/3 (100.0%)
1
LNCaP
Specificity: 0.111
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 59 | C → C | 0.001887 | SNP | Silent | UCEC |
| 206 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 206 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 248 | C → Y | 0.002294 | SNP | Missense Mutation | OV |
| 302 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 393 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 669 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |