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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E5RJ48 LYPLA1 Acyl-protein thioesterase 1 (EC 3.1.2.22) … Homo sapiens (Human) 90 aa

Protein Details: E5RJ48 (LYPLA1)

Protein Information
AccessionE5RJ48
Protein NamesAcyl-protein thioesterase 1 (EC 3.1.2.22) (Lysophospholipase 1) (Lysophospholipase I) (Palmitoyl-protein hydrolase)
Gene SymbolLYPLA1
OrganismHomo sapiens (Human)
Length90 aa
IsoformsNo isoforms
Related PMIDs 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNVAMPSWFD11IIGLSPDSQE21DESGIKQAAE31NIKALIDQEV41KNGIPSNRII
51-9051LGGFSQGGAL61SLYTALTTQQ71KLAGVTALSC81WLPLRASFPQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
80 SWISSPALM DBPTM CYSMODDB Phospholipase/Carboxylesterase
HeLa (29575903)
Unknown (32651440)
GPS-Palm: 0.94
Deep-Palm: 0.30
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine