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UniProt ID Gene Symbol Protein Name Organism Length Action
E5RJB9 PABPC1 Polyadenylate-binding protein 1 Homo sapiens (Human) 129 aa

Protein Details: E5RJB9 (PABPC1)

Protein Information
AccessionE5RJB9
Protein NamesPolyadenylate-binding protein 1
Gene SymbolPABPC1
OrganismHomo sapiens (Human)
Length129 aa
IsoformsNo isoforms
Related PMIDs 31251020
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNPSAPSYPM11ASLYVGDLHP21DVTEAMLYEK31FSPAGPILSI41RVCRDMITRR
51-10051SLGYAYVNFQ61QPADAERALD71TMNFDVIKGK81PVRIMWSQRD91PSLRKSGVGN
101-129101IFIKNLDKSI111DNKALYDTFS121AFGNILSCK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
43 RNA BINDING PROTEIN Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain - -
GPS-Palm: 0.90
Deep-Palm: 0.85
128 SWISSPALM DBPTM CYSMODDB - -
Unknown (32651440)
GPS-Palm: 0.97
Deep-Palm: 0.03
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
43 C → C 0.002288 SNP Silent STAD
67 R → C 0.001887 SNP Missense Mutation UCEC
83 R → C 0.002506 SNP Missense Mutation COAD
206 R → C 0.001887 SNP Missense Mutation UCEC
309 R → C 0.001887 SNP Missense Mutation UCEC
455 R → C 0.001014 SNP Missense Mutation BRCA
518 R → C 0.002141 SNP Missense Mutation SKCM
518 R → C 0.003774 SNP Missense Mutation UCEC
604 R → C 0.002141 SNP Missense Mutation SKCM