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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E5RJF5 ANXA6 Annexin Homo sapiens (Human) 129 aa

Protein Details: E5RJF5 (ANXA6)

Protein Information
Accession E5RJF5
Protein Names Annexin
Gene Symbol ANXA6
Organism Homo sapiens (Human)
Length 129 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
4
PC3 cells
Specificity: 0.143
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MKGFGSDKEA11ILDIITSRSN21RQRQEVCQSY31KSLYGKDLIA41DLKYELTGKF
51-10051ERLIVGLMRP61PAYCDAKEIK71DAISGIGTDE81KCLIEILASR91TNEQMHQLVA
101-129101AYKDAYERDL111EADIIGDTSG121HFQKMLVVL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
64 Prediction (Medium) - -
82 CYSMODDB SWISSPALM DBPTM Prediction (Low) Annexin -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
59 C → C 0.001887 SNP Silent UCEC
206 R → C 0.002506 SNP Missense Mutation COAD
206 R → C 0.001887 SNP Missense Mutation UCEC
248 C → Y 0.002294 SNP Missense Mutation OV
302 Y → C 0.001014 SNP Missense Mutation BRCA
393 R → C 0.001887 SNP Missense Mutation UCEC
669 C → R 0.001887 SNP Missense Mutation UCEC