Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E5RK87 ADAM7 ADAM metallopeptidase domain 7 Homo sapiens (Human) 516 aa

Protein Details: E5RK87 (ADAM7)

Protein Information
AccessionE5RK87
Protein NamesADAM metallopeptidase domain 7
Gene SymbolADAM7
OrganismHomo sapiens (Human)
Length516 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVNFVNMIYK11TLNIHVTLVG21IEIWTHEDKI31ELYSNIETTL41LRFSFWQEKI
51-10051LKTRKDFDHV61VLLSGKWLYS71HVQGISYPGG81MCLPYYSTSI91IKDLLPDTNI
101-150101IANRMAHQLG111HNLGMQHDEF121PCTCPSGKCV131MDSDGSIPAL141KFSKCSQNQY
151-200151HQYLKDYKPT161CMLNIPFPYN171FHDFQFCGNK181KLDEGEECDC191GPAQECTNPC
201-250201CDAHTCVLKP211GFTCAEGECC221ESCQIKKAGS231ICRPAKDECD241FPEMCTGHSP
251-300251ACPKDQFRVN261GFPCKNSEGY271CFMGKCPTRE281DQCSELFDDE291AIESHDICYK
301-350301MNTKGNKFGY311CKNKENRFLP321CEEKDVRCGK331IYCTGGELSS341LLGEDKTYHL
351-400351KDPQKNATVK361CKTIFLYHDS371TDIGLVASGT381KCGEGMVCNN391GECLNMEKVY
401-450401ISTNCPSQCN411ENPVDGHGLQ421CHCEEGQAPV431ACEETLHVTN441ITILVVVLVL
451-500451VIVGIGVLIL461LVRYRKCIKL471KQVQSPPTET481LGVENKGYFG491DEQQIRTEPI
501-516501LPEIHFLNHL511LYGRHQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
82 - - -
Deep-Palm: 0.43
122 - - -
Deep-Palm: 0.03
124 - - -
Deep-Palm: 0.04
129 - - -
Deep-Palm: 0.06
145 - - -
GPS-Palm: 0.71
Deep-Palm: 0.16
161 - - -
Deep-Palm: 0.02
177 - - -
Deep-Palm: 0.03
188 - - -
Deep-Palm: 0.04
190 - - -
Deep-Palm: 0.04
196 - - -
Deep-Palm: 0.10
200 - - -
Deep-Palm: 0.03
201 - - -
Deep-Palm: 0.03
206 - - -
Deep-Palm: 0.04
214 - - -
Deep-Palm: 0.10
219 - - -
Deep-Palm: 0.13
220 - - -
Deep-Palm: 0.21
223 - - -
Deep-Palm: 0.37
232 SWISSPALM DBPTM CYSMODDB Disintegrin - -
GPS-Palm: 0.66
Deep-Palm: 0.05
239 - - -
Deep-Palm: 0.07
245 - - -
Deep-Palm: 0.05
252 - - -
Deep-Palm: 0.02
264 - - -
Deep-Palm: 0.11
271 - - -
Deep-Palm: 0.10
276 - - -
Deep-Palm: 0.06
283 - - -
Deep-Palm: 0.04
298 - - -
Deep-Palm: 0.05
311 - - -
GPS-Palm: 0.79
Deep-Palm: 0.07
321 - - -
GPS-Palm: 0.74
Deep-Palm: 0.24
328 - - -
Deep-Palm: 0.93
333 - - -
Deep-Palm: 0.93
361 - - -
Deep-Palm: 0.33
382 - - -
Deep-Palm: 0.30
388 - - -
Deep-Palm: 0.65
393 - - -
Deep-Palm: 0.06
405 - - -
Deep-Palm: 0.04
409 - - -
Deep-Palm: 0.02
421 - - -
Deep-Palm: 0.05
423 - - -
Deep-Palm: 0.04
432 - - -
Deep-Palm: 0.14
467 - - -
GPS-Palm: 0.90
Deep-Palm: 0.98
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
31 R → C 0.002506 SNP Missense Mutation COAD
31 R → C 0.004283 SNP Missense Mutation SKCM
107 C → C 0.002506 SNP Silent COAD
186 S → C 0.001969 SNP Missense Mutation HNSC
213 R → C 0.002141 SNP Missense Mutation SKCM
310 C → F 0.001764 SNP Missense Mutation LUAD
357 C → C 0.002506 SNP Silent COAD
389 C → R 0.001887 SNP Missense Mutation UCEC
434 C → C 0.001887 SNP Silent UCEC
498 Y → C 0.002747 SNP Missense Mutation LIHC
499 C → C 0.001887 SNP Silent UCEC
526 C → Y 0.001887 SNP Missense Mutation UCEC
633 C → Y 0.002288 SNP Missense Mutation STAD
691 R → C 0.008565 SNP Missense Mutation SKCM
695 C → F 0.002288 SNP Missense Mutation STAD
649* C → ? 0.002545 SNP Nonsense Mutation GBM