Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E7END7 | RAB1A | RAB1A, member RAS oncogene family | Homo sapiens (Human) | 173 aa |
Protein Details: E7END7 (RAB1A)
Protein Information
| Accession | E7END7 |
|---|---|
| Protein Names | RAB1A, member RAS oncogene family |
| Gene Symbol | RAB1A |
| Organism | Homo sapiens (Human) |
| Length | 173 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSSMNPEYDY11LFKLLLIGDS21GVGKSCLLLR31FAWDTAGQER41FRTITSSYYR
51-10051GAHGIIVVYD61VTDQESFNNV71KQWLQEIDRY81ASENVNKLLV91GNKCDLTTKK
101-150101VVDYTTAKEF111ADSLGIPFLE121TSAKNATNVE131QSFMTMAAEI141KKRMGPGATA
151-173151GGAEKSNVKI161QSTPVKQSGG171GCC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 26 | SWISSPALM DBPTM CYSMODDB | Ras family Rab GTPases family involved in membrane trafficking P-loop containing nucleoside triphosphate hydrolase Small GTPase | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.98
|
| 94 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.96
|
|
| 172 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 173 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
LNCaP
Specificity: 0.667
2/2 (100.0%)
1
DU145 cell
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 184 | G → C | 0.001014 | SNP | Missense Mutation | BRCA |