Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E7ERJ7 | PABPC1 | Polyadenylate-binding protein (PABP) | Homo sapiens (Human) | 604 aa |
Protein Details: E7ERJ7 (PABPC1)
Protein Information
| Accession | E7ERJ7 |
|---|---|
| Protein Names | Polyadenylate-binding protein (PABP) |
| Gene Symbol | PABPC1 |
| Organism | Homo sapiens (Human) |
| Length | 604 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.875
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.875
35/46 (76.1%)
4
PC3 cells
Specificity: 0.100
4/4 (100.0%)
1
U937 cells
Specificity: 0.025
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNPSAPSYPM11ASLYVGDLHP21DVTEAMLYEK31FSPAGPILSI41RVCRDMITRR
51-10051SLGYAYVNFQ61QPADAERALD71TMNFDVIKGK81PVRIMWSQRD91PSLRKSGVVC
101-150101DENGSKGYGF111VHFETQEAAE121RAIEKMNGML131LNDRKVFVGR141FKSRKEREAE
151-200151LGARAKEFTN161VYIKNFGEDM171DDERLKDLFG181KFGPALSVKV191MTDESGKSKG
201-250201FGFVSFERHE211DAQKAVDEMN221GKELNGKQIY231VGRAQKKVER241QTELKRKFEQ
251-300251MKQDRITRYQ261GVNLYVKNLD271DGIDDERLRK281EFSPFGTITS291AKVMMEGGRS
301-350301KGFGFVCFSS311PEEATKAVTE321MNGRIVATKP331LYVALAQRKE341ERQAHLTNQY
351-400351MQRMASVRAV361PNPVINPYQP371APPSGYFMAA381IPQTQNRAAY391YPPSQIAQLR
401-450401PSPRWTAQGA411RPHPFQNMPG421AIRPAAPRPP431FSTMRPASSQ441VPRVMSTQRV
451-500451ANTSTQTMGP461RPAAAAAAAT471PAVRTVPQYK481YAAGVRNPQQ491HLNAQPQVTM
501-550501QQPAVHVQGQ511EPLTASMLAS521APPQEQKQML531GERLFPLIQA541MHPTLAGKIT
551-600551GMLLEIDNSE561LLHMLESPES571LRSKVDEAVA581VLQAHQAKEA591AQKAVNSATG
601-604601VPTV
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 43 | Prediction (High) | - | - |
| 307 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | RNA recognition motif | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 43 | C → C | 0.002288 | SNP | Silent | STAD |
| 67 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 83 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 206 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 309 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 455 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 518 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 518 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 604 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |