Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E7ERL0 | NME1 | nucleoside-diphosphate kinase (EC 2.7.4.6) | Homo sapiens (Human) | 139 aa |
Protein Details: E7ERL0 (NME1)
Protein Information
| Accession | E7ERL0 |
|---|---|
| Protein Names | nucleoside-diphosphate kinase (EC 2.7.4.6) |
| Gene Symbol | NME1 |
| Organism | Homo sapiens (Human) |
| Length | 139 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVLLSTLGIV11FQGEGPPISS21CDTGTMANCE31RTFIAIKPDG41VQRGLVGEII
51-10051KRFEQKGFRL61VGLKFMQASE71DLLKEHYVDL81KDRPFFAGLV91KYMHSGPVVA
101-139101MVWEGLNVVK111TGRVMLGETN121PADSKPGTIR131GDFCIQVGR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 21 | - | - | - |
Deep-Palm: 0.57
|
|
| 29 | Nucleoside diphosphate kinase-like domain superfamily Nucleoside diphosphate kinase-like domain | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.76
|
|
| 134 | SWISSPALM DBPTM CYSMODDB | Nucleoside diphosphate kinase |
HeLa
(29575903)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.95
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
PC3
Specificity: 0.571
4/4 (100.0%)
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| ? | ? → ? | 0.002427 | SNP | Missense Mutation | BLCA |