Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E7ERP7 | APOE | Apolipoprotein E | Homo sapiens (Human) | 219 aa |
Protein Details: E7ERP7 (APOE)
Protein Information
| Accession | E7ERP7 |
|---|---|
| Protein Names | Apolipoprotein E |
| Gene Symbol | APOE |
| Organism | Homo sapiens (Human) |
| Length | 219 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKVLWAALLV11TFLAGCQAKV21EQAVETEPEP31ELRQQTEWQS41GQRWELALGR
51-10051FWDYLRWVQT61LSEQVQEELL71SSQVTQELRA81LMDETMKELK91AYKSELEEQL
101-150101TPVAEETRAR111LSKELQAAQA121RLGADMEDVC131GRLVQYRGEV141QAMLGQSTEE
151-200151LRVRLASHLR161KLRKRLLRDA171DDLQKRLAVY181QAGAREGAER191GLSAIRERLG
201-219201PLVEQGRVRA211ATVGSLAGQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 16 | Prokaryotic membrane lipoprotein lipid attachment site profile. | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.95
|
|
| 130 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
frontal cortex
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 56 | R → C | 0.002288 | SNP | Missense Mutation | STAD |