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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E7ESH4 HSPD1 60 kDa heat shock protein, … Homo sapiens (Human) 231 aa

Protein Details: E7ESH4 (HSPD1)

Protein Information
AccessionE7ESH4
Protein Names60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (Heat shock protein 60)
Gene SymbolHSPD1
OrganismHomo sapiens (Human)
Length231 aa
IsoformsNo isoforms
Related PMIDs 21076176 22496122 31251020 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLRLPTVFRQ11MRPVSRVLAP21HLTRAYAKDV31KFGADARALM41LQGVDLLADA
51-10051VAVTMGPKGR61TVIIEQSWGS71PKVTKDGVTV81AKSIDLKDKY91KNIGAKLVQD
101-150101VANNTNEEAG111DGTTTATVLA121RSIAKEGFEK131ISKGANPVEI141RRGVMLAVDA
151-200151VIAELKKQSK161PVTTPEEIAQ171VATISANGDK181EIGNIISDAM191KKVGRKGVIT
201-231201DGKTLNDELE211IIEGMKFDRG221YISPYFINTS231K
Palmitoylation Sites Details

No known palmitoylation sites

Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
3
LNCaP
Specificity: 0.333
3/3 (100.0%)
1
Jurkat T cell
Specificity: 0.111
1/1 (100.0%)
1
EC cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
362 G → C 0.001014 SNP Missense Mutation BRCA
370 R → C 0.002506 SNP Missense Mutation COAD
370 R → C 0.002020 SNP Missense Mutation PRAD
370 R → C 0.003774 SNP Missense Mutation UCEC