Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E7EUT5 GAPDH glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) … Homo sapiens (Human) 260 aa

Protein Details: E7EUT5 (GAPDH)

Protein Information
Accession E7EUT5
Protein Names glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (EC 1.2.1.12) (Peptidyl-cysteine S-nitrosylase GAPDH)
Gene Symbol GAPDH
Organism Homo sapiens (Human)
Length 260 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.900
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.900
36/46 (78.3%)
4
PC3 cells
Specificity: 0.100
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEEMRDPSKI11KWGDAGAEYV21VESTGVFTTM31EKAGAHLQGG41AKRVIISAPS
51-10051ADAPMFVMGV61NHEKYDNSLK71IISNASCTTN81CLAPLAKVIH91DNFGIVEGLM
101-150101TTVHAITATQ111KTVDGPSGKL121WRDGRGALQN131IIPASTGAAK141AVGKVIPELN
151-200151GKLTGMAFRV161PTANVSVVDL171TCRLEKPAKY181DDIKKVVKQA191SEGPLKGILG
201-250201YTEHQVVSSD211FNSDTHSSTF221DAGAGIALND231HFVKLISWYD241NEFGYSNRVV
251-260251DLMAHMASKE
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
77 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
81 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Glyceraldehyde 3-phosphate dehydrogenase C-terminal domain -
172 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Glyceraldehyde 3-phosphate dehydrogenase C-terminal domain -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
16 R → C 0.001887 SNP Missense Mutation UCEC