Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E7EW28 | SLC4A10 | Anion exchange protein | Homo sapiens (Human) | 1054 aa |
Protein Details: E7EW28 (SLC4A10)
Protein Information
| Accession | E7EW28 |
|---|---|
| Protein Names | Anion exchange protein |
| Gene Symbol | SLC4A10 |
| Organism | Homo sapiens (Human) |
| Length | 1054 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
Cerebral cortex
Specificity: 0.750
3/4 (75.0%)
1
Prefrontal cortex
Specificity: 0.250
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEIKDQGAQM11EPLLPTRNDE21EAVVDRGGTR31SILKTHFEKE41DLEGHRTLFI
51-10051GVHVPLGGRK61SHRRHRHRGH71KHRKRDRERD81SGLEDGRESP91SFDTPSQRVQ
101-150101FILGTEDDDE111EHIPHDLFTE121LDEICWREGE131DAEWRETARW141LKFEEDVEDG
151-200151GERWSKPYVA161TLSLHSLFEL171RSCILNGTVL181LDMHANTLEE191IADMVLDQQV
201-250201SSGQLNEDVR211HRVHEALMKQ221HHHQNQKKLT231NRIPIVRSFA241DIGKKQSEPN
251-300251SMDKNAGQVV261SPQSAPACVE271NKNDVSRENS281TVDFSKGLGG291QQKGHTSPCG
301-350301MKQRHEKGPP311HQQEREVDLH321FMKKIPPGAE331ASNILVGELE341FLDRTVVAFV
351-400351RLSPAVLLQG361LAEVPIPTRF371LFILLGPLGK381GQQYHEIGRS391IATLMTDEVF
401-450401HDVAYKAKDR411NDLVSGIDEF421LDQVTVLPPG431EWDPSIRIEP441PKNVPSQEKR
451-500451KIPAVPNGTA461AHGEAEPHGG471HSGPELQRTG481RIFGGLILDI491KRKAPYFWSD
501-550501FRDAFSLQCL511ASFLFLYCAC521MSPVITFGGL531LGEATEGRIS541AIESLFGASM
551-600551TGIAYSLFGG561QPLTILGSTG571PVLVFEKILF581KFCKEYGLSY591LSLRASIGLW
601-650601TATLCIILVA611TDASSLVCYI621TRFTEEAFAS631LICIIFIYEA641LEKLFELSEA
651-700651YPINMHNDLE661LLTQYSCNCV671EPHNPSNGTL681KEWRESNISA691SDIIWENLTV
701-750701SECKSLHGEY711VGRACGHDHP721YVPDVLFWSV731ILFFSTVTLS741ATLKQFKTSR
751-800751YFPTKVRSIV761SDFAVFLTIL771CMVLIDYAIG781IPSPKLQVPS791VFKPTRDDRG
801-850801WFVTPLGPNP811WWTVIAAIIP821ALLCTILIFM831DQQITAVIIN841RKEHKLKKGC
851-900851GYHLDLLMVA861VMLGVCSIMG871LPWFVAATVL881SITHVNSLKL891ESECSAPGEQ
901-950901PKFLGIREQR911VTGLMIFILM921GSSVFMTSIL931KFIPMPVLYG941VFLYMGASSL
951-1000951KGIQFFDRIK961LFWMPAKHQP971DFIYLRHVPL981RKVHLFTIIQ991MSCLGLLWII
1001-10501001KVSRAAIVFP1011MMVLALVFVR1021KLMDLLFTKR1031ELSWLDDLMP1041ESKKKKLEDA
1051-10541051EKEH
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 125 | Prediction (Low) | - | - |
| 173 | Prediction (Medium) | - | - |
| 583 | Prediction (Medium) | - | - |
| 618 | Prediction (Low) | - | - |
| 633 | Prediction (Low) | - | - |
| 703 | Prediction (Low) | - | - |
| 993 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 30 | R → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 30 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 127 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |
| 210 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 237 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 237 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 410 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 410 | R → C | 0.008565 | SNP | Missense Mutation | SKCM |
| 509 | C → R | 0.001014 | SNP | Missense Mutation | BRCA |
| 538 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 583 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 618 | C → C | 0.001887 | SNP | Silent | UCEC |
| 799 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 928 | S → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 993 | C → C | 0.001887 | SNP | Silent | UCEC |