Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PAM4 N/A Phosphatidylinositol 4-kinase type 2 (EC … Homo sapiens (Human) 449 aa

Protein Details: E9PAM4

Protein Information
AccessionE9PAM4
Protein NamesPhosphatidylinositol 4-kinase type 2 (EC 2.7.1.67)
Gene SymbolNot available
OrganismHomo sapiens (Human)
Length449 aa
IsoformsNo isoforms
Related PMIDs 31251020 32651440 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTM
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLGPQVWSSV11RQGLSRSLSR21NVGVWASGEG31KKVDIAGIYP41PVTTPFTATA
51-10051EVDYGKLEEN61LHKLGTFPFR71GAVGGVCALA81NVLGAQVCQL91ERLCCTGQWE
101-150101DAQKLQHRLI111EPNAARIIAV121FKPKNEEPYG131HLNPKWTKWL141QKLCCPCCFG
151-200151RDCLVLNQGY161LSEAGASLVD171QKLELNIVPR181TKVVYLASET191FNYSAIDRVK
201-250201SRGKRLALEK211VPKVGQRFNR221IGLPPKVGSF231QLFVEGYKDA241DYWLRRFEAE
251-300251PLPENTNRQL261LLQFERLVVL271DYIIRNTDRG281NDNWLIKYDC291PMDSSSSRDT
301-350301DWVVVKEPVI311KVAAIDNGLA321FPLKHPDSWR331AYPFYWAWLP341QAKVPFSQEI
351-400351KDLILPKISD361PNFVKDLEED371LYELFKKDPG381FDRGQFHKQI391AVMRGQILNL
401-449401TQALKDNKSP411LHLVQMPPVI421VETARSHQRS431SSESYTQSFQ441SRKPFFSWW
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
77 - - -
GPS-Palm: 0.69
Deep-Palm: 0.98
88 - - -
GPS-Palm: 0.68
Deep-Palm: 0.92
94 - - -
GPS-Palm: 0.86
Deep-Palm: 0.89
95 - - -
GPS-Palm: 0.70
Deep-Palm: 0.90
144 - - -
GPS-Palm: 0.97
Deep-Palm: 0.24
145 - - -
GPS-Palm: 0.97
Deep-Palm: 0.35
147 - - -
GPS-Palm: 0.97
Deep-Palm: 0.46
148 - - -
GPS-Palm: 0.97
Deep-Palm: 0.55
153 - -
LNCaP (31251020)
GPS-Palm: 0.88
Deep-Palm: 0.90
290 SWISSPALM DBPTM CYSMODDB Phosphatidylinositol 3- and 4-kinase -
LNCaP (31251020)
Deep-Palm: 0.08
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
LNCaP
Specificity: 0.600
3/3 (100.0%)
1
Jurkat T cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.200
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine