Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PCA1 | CCT5 | T-complex protein 1 subunit epsilon … | Homo sapiens (Human) | 520 aa |
Protein Details: E9PCA1 (CCT5)
Protein Information
| Accession | E9PCA1 |
|---|---|
| Protein Names | T-complex protein 1 subunit epsilon (CCT-epsilon) |
| Gene Symbol | CCT5 |
| Organism | Homo sapiens (Human) |
| Length | 520 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 22496122 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.727
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.727
24/46 (52.2%)
4
Jurkat T cells
Specificity: 0.121
4/25 (16.0%)
4
PC3 cells
Specificity: 0.121
4/4 (100.0%)
1
Endothelial cells
Specificity: 0.030
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNSSLGPTIE11KLSVSHIMAA21KAVANTMRTS31LGPNGLDKMM41VDKDGDVTVT
51-10051NDGATILSMM61DVDHQIAKLM71VELSKSQDDE81IGDGTTGVVV91LAGALLEEAE
101-150101QLLDRGIHPI111RIADGYEQAA121RVAIEHLDKI131SDSVLVDIKD141TEPLIQTAKT
151-200151TLGSKVVNSC161HRQMAEIAVN171AVLTVADMER181RDVDFELIKV191EGKVGGRLED
201-250201TKLIKGVIVD211KDFSHPQMPK221KVEDAKIAIL231TCPFEPPKPK241TKHKLDVTSV
251-300251EDYKALQKYE261KEKFEEMIQQ271IKETGANLAI281CQWGFDDEAN291HLLLQNNLPA
301-350301VRWVGGPEIE311LIAIATGGRI321VPRFSELTAE331KLGFAGLVQE341ISFGTTKDKM
351-400351LVIEQCKNSR361AVTIFIRGGN371KMIIEEAKRS381LHDALCVIRN391LIRDNRVVYG
401-450401GGAAEISCAL411AVSQEADKCP421TLEQYAMRAF431ADALEVIPMA441LSENSGMNPI
451-500451QTMTEVRARQ461VKEMNPALGI471DCLHKGTNDM481KQQHVIETLI491GKKQQISLAT
501-520501QMVRMILKID511DIRKPGESEE
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 160 | Prediction (Medium) | - | - |
| 232 | CYSMODDB SWISSPALM DBPTM Prediction (High) | TCP-1/cpn60 chaperonin family | - |
| 281 | Prediction (High) | - | - |
| 386 | Prediction (High) | - | - |
| 408 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 12 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 386 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 429 | C → C | 0.027027 | SNP | Silent | DLBC |
| 534 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |