Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PCR7 | OGDH | 2-oxoglutarate dehydrogenase complex component E1 … | Homo sapiens (Human) | 1038 aa |
Protein Details: E9PCR7 (OGDH)
Protein Information
| Accession | E9PCR7 |
|---|---|
| Protein Names | 2-oxoglutarate dehydrogenase complex component E1 (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase) |
| Gene Symbol | OGDH |
| Organism | Homo sapiens (Human) |
| Length | 1038 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 31382980 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.800
36/46 (78.3%)
4
Cerebral cortex
Specificity: 0.089
4/4 (100.0%)
3
PC3 cells
Specificity: 0.067
3/4 (75.0%)
1
U937 cells
Specificity: 0.022
1/1 (100.0%)
1
DU145 cells
Specificity: 0.022
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFHLRTCAAK11LRPLTASQTV21KTFSQNRPAA31ARTFQQIRCY41SAPVAAEPFL
51-10051SGTSSNYVEE61MYCAWLENPK71SVHKSWDIFF81RNTNAGAPPG91TAYQSPLPLS
101-150101RGSLAAVAHA111QSLVEAQPNV121DKLVEDHLAV131QSLIRAYQIR141GHHVAQLDPL
151-200151GILDADLDSS161VPADIISSTD171KLDLAVFKER181LRMLTVGGFY191GLDESDLDKV
201-250201FHLPTTTFIG211GQESALPLRE221IIRRLEMAYC231QHIGVEFMFI241NDLEQCQWIR
251-300251QKFETPGIMQ261FTNEEKRTLL271ARLVRSTRFE281EFLQRKWSSE291KRFGLEGCEV
301-350301LIPALKTIID311KSSENGVDYV321IMGMPHRGRL331NVLANVIRKE341LEQIFCQFDS
351-400351KLEAADEGSG361DVKYHLGMYH371RRINRVTDRN381ITLSLVANPS391HLEAADPVVM
401-450401GKTKAEQFYC411GDTEGKKVMS421ILLHGDAAFA431GQGIVYETFH441LSDLPSYTTH
451-500451GTVHVVVNNQ461IGFTTDPRMA471RSSPYPTDVA481RVVNAPIFHV491NSDDPEAVMY
501-550501VCKVAAEWRS511TFHKDVVVDL521VCYRRNGHNE531MDEPMFTQPL541MYKQIRKQKP
551-600551VLQKYAELLV561SQGVVNQPEY571EEEISKYDKI581CEEAFARSKD591EKILHIKHWL
601-650601DSPWPGFFTL611DGQPRSMSCP621STGLTEDILT631HIGNVASSVP641VENFTIHGGL
651-700651SRILKTRGEM661VKNRTVDWAL671AEYMAFGSLL681KEGIHIRLSG691QDVERGTFSH
701-750701RHHVLHDQNV711DKRTCIPMNH721LWPNQAPYTV731CNSSLSEYGV741LGFELGFAMA
751-800751SPNALVLWEA761QFGDFHNTAQ771CIIDQFICPG781QAKWVRQNGI791VLLLPHGMEG
801-850801MGPEHSSARP811ERFLQMCNDD821PDVLPDLKEA831NFDINQLYDC841NWVVVNCSTP
851-900851GNFFHVLRRQ861ILLPFRKPLI871IFTPKSLLRH881PEARSSFDEM891LPGTHFQRVI
901-950901PEDGPAAQNP911ENVKRLLFCT921GKVYYDLTRE931RKARDMVGQV941AITRIEQLSP
951-1000951FPFDLLLKEV961QKYPNAELAW971CQEEHKNQGY981YDYVKPRLRT991TISRAKPVWY
1001-10381001AGRDPAAAPA1011TGNKKTHLTE1021LQRLLDTAFD1031LDVFKNFS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 7 | Prediction (High) | - | - |
| 39 | Prediction (Low) | - | - |
| 230 | Prediction (Low) | - | - |
| 246 | Prediction (Medium) | - | - |
| 298 | Prediction (High) | - | - |
| 346 | Prediction (Medium) | - | - |
| 410 | Prediction (Low) | - | - |
| 522 | Prediction (Medium) | - | - |
| 581 | Prediction (Medium) | - | - |
| 619 | Prediction (Medium) | - | - |
| 778 | Prediction (Low) | - | - |
| 919 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 41 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 81 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 81 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 277 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 283 | C → C | 0.001887 | SNP | Silent | UCEC |
| 604 | C → C | 0.001764 | SNP | Silent | LUAD |
| 653 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 686 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 700 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 713 | Y → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 769 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 794 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 864 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 904 | C → C | 0.001969 | SNP | Silent | LGG |
| 909 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |