Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PCT5 | CAV1 | Caveolin | Homo sapiens (Human) | 167 aa |
Protein Details: E9PCT5 (CAV1)
Protein Information
| Accession | E9PCT5 |
|---|---|
| Protein Names | Caveolin |
| Gene Symbol | CAV1 |
| Organism | Homo sapiens (Human) |
| Length | 167 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 29575903 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
PC3 cells
Specificity: 0.571
4/4 (100.0%)
2
DU145 cells
Specificity: 0.286
2/2 (100.0%)
1
HeLa cells
Specificity: 0.143
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSGGKYVDSE11GNIYKPNNKA21MADELSEKQV31YDAHTKEIDL41VNRDPKHLND
51-10051DVVKIDFEDV61IAEPEGTHSF71DGIWKASFTT81FTVTKYWFYR91LLSALFGIPM
101-150101ALIWGIYFAI111LSFLHIWAVV121PCIKSFLIEI131QCISRVYSIY141VHTVCDPLFE
151-167151AVGKIFSNVR161INLQKEI
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 122 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Caveolin | - |
| 132 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Caveolin | - |
| 145 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | Caveolin | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 146 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 171 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 171 | R → C | 0.005435 | SNP | Missense Mutation | ESCA |