Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PCX2 | AKR1B1 | aldose reductase (EC 1.1.1.21) (Aldehyde … | Homo sapiens (Human) | 263 aa |
Protein Details: E9PCX2 (AKR1B1)
Protein Information
| Accession | E9PCX2 |
|---|---|
| Protein Names | aldose reductase (EC 1.1.1.21) (Aldehyde reductase) |
| Gene Symbol | AKR1B1 |
| Organism | Homo sapiens (Human) |
| Length | 263 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASRLLLNNG11AKMPILGLGT21WKSPPGQVTE31AVKVAIDVGY41RHIDCAHVYQ
51-10051NENEVGVAIQ61EKLREQVVKR71EELFIVSKLW81CTYHEKGLVK91GACQKTLSDL
101-150101KLDYLDLYLI111HWPTGFKPGK121EFFPLDESGN131VVPSDTNILD141TWAAMEELVD
151-200151EGLVKAIGIS161NFNHLQVEMI171LNKPGLKYKP181AVNQIECHPY191LTQEKLIQYC
201-250201QSKGIVVTAY211SPLGSPDRPW221AKPEDPSLLE231DPRIKAIAAK241HNKTTAQVQP
251-263251LQVLLTVHNC261LHS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 81 | Prediction (Medium) | - | - |
| 93 | Prediction (Medium) | - | - |
| 200 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | Aldo/keto reductase family | - |
| 260 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 104 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 158 | G → C | 0.002294 | SNP | Missense Mutation | OV |
| 269 | R → C | 0.002294 | SNP | Missense Mutation | OV |
| 279 | F → delinsC*DLKI | 0.001887 | INS | Nonsense Mutation | UCEC |