Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PDW2 | OXCT1 | 3-oxoacid CoA-transferase 1 | Homo sapiens (Human) | 334 aa |
Protein Details: E9PDW2 (OXCT1)
Protein Information
| Accession | E9PDW2 |
|---|---|
| Protein Names | 3-oxoacid CoA-transferase 1 |
| Gene Symbol | OXCT1 |
| Organism | Homo sapiens (Human) |
| Length | 334 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MMVREFNGQH11FILEEAITGD21FALVKAWKAD31RAGNVIFRKS41ARNFNLPMCK
51-10051AAETTVVEVE61EIVDIGAFAP71EDIHIPQIYV81HRLIKGEKYE91KRIERLSIRK
101-150101EGDGEAKSAK111PGDDVRERII121KRAALEFEDG131MYANLGIGIP141LLASNFISPN
151-200151ITVHLQSENG161VLGLGPYPRQ171HEADADLINA181GKETVTILPG191ASFFSSDESF
201-250201AMIRGGHVDL211TMLGAMQVSK221YGDLANWMIP231GKMVKGMGGA241MDLVSSAKTK
251-300251VVVTMEHSAK261GNAHKIMEKC271TLPLTGKQCV281NRIITEKAVF291DVDKKKGLTL
301-334301IELWEGLTVD311DVQKSTGCDF321AVSPKLMPMQ331QIAN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 49 | NagB/RpiA transferase-like Coenzyme A transferase family I | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.88
|
|
| 270 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.50
|
|
| 279 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.66
|
|
| 318 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.81
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
LNCaP
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
PC3
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 14 | C → R | 0.027027 | SNP | Missense Mutation | DLBC |
| 30 | C → Ffs*18 | 0.001887 | DEL | Frame Shift Del | UCEC |
| 67 | C → C | 0.001887 | SNP | Silent | UCEC |
| 110 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 146 | R → C | 0.007299 | SNP | Missense Mutation | READ |
| 343 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |