Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PEW0 USP36 Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) Homo sapiens (Human) 548 aa

Protein Details: E9PEW0 (USP36)

Protein Information
AccessionE9PEW0
Protein NamesUbiquitin carboxyl-terminal hydrolase (EC 3.4.19.12)
Gene SymbolUSP36
OrganismHomo sapiens (Human)
Length548 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPIVDKLKEA11LKPGRKDSAD21DGELGKLLAS31SAKKVLLQKI41EFEPASKSFS
51-10051YQLEALKSKY61VLLNPKTEGA71SRHKSGDDPP81ARRQGSEHTY91ESCGDGVPAP
101-150101QKVLFPTERL111SLRWERVFRV121GAGLHNLGNT131CFLNATIQCL141TYTPPLANYL
151-200151LSKEHARSCH161QGSFCMLCVM171QNHIVQAFAN181SGNAIKPVSF191IRDLKKIARH
201-250201FRFGNQEDAH211EFLRYTIDAM221QKACLNGCAK231LDRQTQATTL241VHQIFGGYLR
251-300251SRVKCSVCKS261VSDTYDPYLD271VALEIRQAAN281IVRALELFVK291ADVLSGENAY
301-350301MCAKCKKKVP311ASKRFTIHRT321SNVLTLSLKR331FANFSGGKIT341KDVGYPEFLN
351-400351IRPYMSQNNG361DPVMYGLYAV371LVHSGYSCHA381GHYYCYVKAS391NGQWYQMNDS
401-450401LVHSSNVKVV411LNQQAYVLFY421LRIPGSKKSP431EGLISRTGSS441SLPGRPSVIP
451-500451DHSKKNIGNG461IISSPLTGKR471QDSGTMKKPH481TTEEIGVPIS491RNGSTLGLKS
501-548501QNGCIPPKLP511SGSPSPKLSQ521TPTHMPTILD531DPGKKVKKPA541PPLPTGMG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
93 - - -
Deep-Palm: 0.91
131 - - -
Deep-Palm: 0.53
139 - - -
Deep-Palm: 0.68
159 - - -
Deep-Palm: 0.13
165 - - -
Deep-Palm: 0.06
168 - - -
Deep-Palm: 0.03
224 - - -
GPS-Palm: 0.93
Deep-Palm: 0.60
228 - - -
GPS-Palm: 0.93
Deep-Palm: 0.61
255 - - -
GPS-Palm: 0.75
Deep-Palm: 0.15
258 - - -
GPS-Palm: 0.73
Deep-Palm: 0.36
302 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.85
Deep-Palm: 0.69
305 - - -
GPS-Palm: 0.84
Deep-Palm: 0.38
378 - - -
Deep-Palm: 0.02
385 - - -
Deep-Palm: 0.01
504 - - -
GPS-Palm: 0.81
Deep-Palm: 0.94
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
119 R → C 0.002288 SNP Missense Mutation STAD
157 R → C 0.005587 SNP Missense Mutation PCPG
202 R → C 0.001969 SNP Missense Mutation HNSC
314 R → C 0.001887 SNP Missense Mutation UCEC
638 C → C 0.001887 SNP Silent UCEC
994 C → Y 0.002288 SNP Missense Mutation STAD
1006 R → C 0.001887 SNP Missense Mutation UCEC
1122 R → C 0.001764 SNP Missense Mutation LUAD
1122 R → C 0.002294 SNP Missense Mutation OV