Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PEW0 USP36 Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12) Homo sapiens (Human) 548 aa

Protein Details: E9PEW0 (USP36)

Protein Information
Accession E9PEW0
Protein Names Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12)
Gene Symbol USP36
Organism Homo sapiens (Human)
Length 548 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
8
LNCaP cells
Specificity: 0.800
8/46 (17.4%)
2
PC3 cells
Specificity: 0.200
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPIVDKLKEA11LKPGRKDSAD21DGELGKLLAS31SAKKVLLQKI41EFEPASKSFS
51-10051YQLEALKSKY61VLLNPKTEGA71SRHKSGDDPP81ARRQGSEHTY91ESCGDGVPAP
101-150101QKVLFPTERL111SLRWERVFRV121GAGLHNLGNT131CFLNATIQCL141TYTPPLANYL
151-200151LSKEHARSCH161QGSFCMLCVM171QNHIVQAFAN181SGNAIKPVSF191IRDLKKIARH
201-250201FRFGNQEDAH211EFLRYTIDAM221QKACLNGCAK231LDRQTQATTL241VHQIFGGYLR
251-300251SRVKCSVCKS261VSDTYDPYLD271VALEIRQAAN281IVRALELFVK291ADVLSGENAY
301-350301MCAKCKKKVP311ASKRFTIHRT321SNVLTLSLKR331FANFSGGKIT341KDVGYPEFLN
351-400351IRPYMSQNNG361DPVMYGLYAV371LVHSGYSCHA381GHYYCYVKAS391NGQWYQMNDS
401-450401LVHSSNVKVV411LNQQAYVLFY421LRIPGSKKSP431EGLISRTGSS441SLPGRPSVIP
451-500451DHSKKNIGNG461IISSPLTGKR471QDSGTMKKPH481TTEEIGVPIS491RNGSTLGLKS
501-548501QNGCIPPKLP511SGSPSPKLSQ521TPTHMPTILD531DPGKKVKKPA541PPLPTGMG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
224 Prediction (High) - -
228 Prediction (High) - -
255 Prediction (Low) - -
258 Prediction (Low) - -
302 CYSMODDB SWISSPALM DBPTM Prediction (Medium) - -
305 Prediction (Medium) - -
504 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
119 R → C 0.002288 SNP Missense Mutation STAD
157 R → C 0.005587 SNP Missense Mutation PCPG
202 R → C 0.001969 SNP Missense Mutation HNSC
314 R → C 0.001887 SNP Missense Mutation UCEC
638 C → C 0.001887 SNP Silent UCEC
994 C → Y 0.002288 SNP Missense Mutation STAD
1006 R → C 0.001887 SNP Missense Mutation UCEC
1122 R → C 0.001764 SNP Missense Mutation LUAD
1122 R → C 0.002294 SNP Missense Mutation OV