Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PFG7 | OGDH | 2-oxoglutarate dehydrogenase complex component E1 … | Homo sapiens (Human) | 873 aa |
Protein Details: E9PFG7 (OGDH)
Protein Information
| Accession | E9PFG7 |
|---|---|
| Protein Names | 2-oxoglutarate dehydrogenase complex component E1 (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase) |
| Gene Symbol | OGDH |
| Organism | Homo sapiens (Human) |
| Length | 873 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
PC3 cells
Specificity: 0.750
3/4 (75.0%)
1
DU145 cells
Specificity: 0.250
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MFHLRTCAAK11LRPLTASQTV21KTFSQNRPAA31ARTFQQIRCY41SAPVAAEPFL
51-10051SGTSSNYVEE61MYCAWLENPK71SVHKGSMAWM81SLTSTRSSTC91PPPLSSGDRN
101-150101QHFLCGRSSV111GWRFEEFLQR121KWSSEKRFGL131EGCEVLIPAL141KTIIDKSSEN
151-200151GVDYVIMGMP161HRGRLNVLAN171VIRKELEQIF181CQFDSKLEAA191DEGSGDVKYH
201-250201LGMYHRRINR211VTDRNITLSL221VANPSHLEAA231DPVVMGKTKA241EQFYCGDTEG
251-300251KKVMSILLHG261DAAFAGQGIV271YETFHLSDLP281SYTTHGTVHV291VVNNQIGFTT
301-350301DPRMARSSPY311PTDVARVVNA321PIFHVNSDDP331EAVMYVCKVA341AEWRSTFHKD
351-400351VVVDLVCYRR361NGHNEMDEPM371FTQPLMYKQI381RKQKPVLQKY391AELLVSQGVV
401-450401NQPEYEEEIS411KYDKICEEAF421ARSKDEKILH431IKHWLDSPWP441GFFTLDGQPR
451-500451SMSCPSTGLT461EDILTHIGNV471ASSVPVENFT481IHGGLSRILK491TRGEMVKNRT
501-550501VDWALAEYMA511FGSLLKEGIH521IRLSGQDVER531GTFSHRHHVL541HDQNVDKRTC
551-600551IPMNHLWPNQ561APYTVCNSSL571SEYGVLGFEL581GFAMASPNAL591VLWEAQFGDF
601-650601HNTAQCIIDQ611FICPGQAKWV621RQNGIVLLLP631HGMEGMGPEH641SSARPERFLQ
651-700651MCNDDPDVLP661DLKEANFDIN671QLYDCNWVVV681NCSTPGNFFH691VLRRQILLPF
701-750701RKPLIIFTPK711SLLRHPEARS721SFDEMLPGTH731FQRVIPEDGP741AAQNPENVKR
751-800751LLFCTGKVYY761DLTRERKARD771MVGQVAITRI781EQLSPFPFDL791LLKEVQKYPN
801-850801AELAWCQEEH811KNQGYYDYVK821PRLRTTISRA831KPVWYAGRDP841AAAPATGNKK
851-873851THLTELQRLL861DTAFDLDVFK871NFS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 7 | Prediction (High) | - | - |
| 39 | Prediction (Low) | - | - |
| 105 | Prediction (Low) | - | - |
| 133 | Prediction (High) | - | - |
| 181 | Prediction (Medium) | - | - |
| 245 | Prediction (Low) | - | - |
| 357 | Prediction (Medium) | - | - |
| 416 | Prediction (Medium) | - | - |
| 454 | Prediction (Medium) | - | - |
| 613 | Prediction (Low) | - | - |
| 754 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 41 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 81 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 81 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 277 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 283 | C → C | 0.001887 | SNP | Silent | UCEC |
| 604 | C → C | 0.001764 | SNP | Silent | LUAD |
| 653 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 686 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 700 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 713 | Y → C | 0.002976 | SNP | Missense Mutation | KIRC |
| 769 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 794 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 864 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 904 | C → C | 0.001969 | SNP | Silent | LGG |
| 909 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |