Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PFP8 | PCBP3 | Poly(rC) binding protein 3 | Homo sapiens (Human) | 361 aa |
Protein Details: E9PFP8 (PCBP3)
Protein Information
| Accession | E9PFP8 |
|---|---|
| Protein Names | Poly(rC) binding protein 3 |
| Gene Symbol | PCBP3 |
| Organism | Homo sapiens (Human) |
| Length | 361 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 1.000
12/46 (26.1%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MESKVSEGGL11NVTLTIRLLM21HGKEVGSIIG31KKGETVKKMR41EESGARINIS
51-10051EGNCPERIVT61ITGPTDAIFK71AFAMIAYKFE81EDIINSMSNS91PATSKPPVTL
101-150101RLVVPASQCG111SLIGKGGSKI121KEIRESTGAQ131VQVAGDMLPN141STERAVTISG
151-200151TPDAIIQCVK161QICVVMLESP171PKGATIPYRP181KPASTPVIFA191GGQVRADPLA
201-250201ASTANLSLLL211QHPPLPAYTI221QGQYAIPHPD231LTKLHQLAMQ241QTPFPPLGQT
251-300251NPAFPGEKLP261LHSSEEAQNL271MGQSSGLDAS281PPASTHELTI291PNDLIGCIIG
301-350301RQGTKINEIR311QMSGAQIKIA321NATEGSSERQ331ITITGTPANI341SLAQYLINAR
351-361351LTSEVTGMGT361L
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 54 | CYSMODDB SWISSPALM DBPTM | KH domain | - |
| 109 | CYSMODDB SWISSPALM DBPTM Prediction (High) | KH domain | - |
| 158 | Prediction (Medium) | - | - |
| 297 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 72 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 190 | C → C | 0.005618 | SNP | Silent | PAAD |
| 221 | F → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 311 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 339 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 190* | C → ? | 0.002747 | SNP | Nonsense Mutation | LIHC |