Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PG35 | MCCC1 | Methylcrotonyl-CoA carboxylase subunit 1 | Homo sapiens (Human) | 598 aa |
Protein Details: E9PG35 (MCCC1)
Protein Information
| Accession | E9PG35 |
|---|---|
| Protein Names | Methylcrotonyl-CoA carboxylase subunit 1 |
| Gene Symbol | MCCC1 |
| Organism | Homo sapiens (Human) |
| Length | 598 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
LNCaP cells
Specificity: 1.000
4/46 (8.7%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAASAVSVL11LVAAERNRWH21RLPSLLLPPR31TWVWRQRTMK41YTTATDEAYS
51-10051IGPAPSQQSY61LSMEKIIQVA71KTSAAQAIHP81GCGFLSENME91FAELCKQEGI
101-150101IFIGPPPSAI111RDMGIKSTSK121SIMAAAGVPV131VEGYHGEDQS141DQCLKEHARR
151-200151IGYPVMIKAV161RGGGGKGMRI171VRSEQEFQEQ181LESARREAKK191SFNDDAMLIE
201-250201KFVDTPRHVE211VQVFGDHHGN221AVYLFERDCS231VQRRHQKIIE241EAPAPGIKSE
251-300251VRKKLGEAAV261RAAKAVNYVG271AGTVEFIMDS281KHNFCFMEMN291TRLQVEHPVT
301-350301EMITGTDLVE311WQLRIAAGEK321IPLSQEEITL331QGHAFEARIY341AEDPSNNFMP
351-400351VAGPLVHLST361PRADPSTRIE371TGVRQGDEVS381VHYDPMIAKL391VVWAADRQAA
401-450401LTKLRYSLRQ411YNIVGLHTNI421DFLLNLSGHP431EFEAGNVHTD441FIPQHHKQLL
451-500451LSRKAAAKES461LCQAALGLIL471KEKAMTDTFT481LQAHDQFSPF491SSSSGRRLNI
501-550501SYTRNMTLKD511GKNNVAIAVT521YNHDGSYSMQ531IEDKTFQVLG541NLYSEGDCTY
551-598551LKCSVNGVAS561KAKLIILENT571IYLFSKEGSI581EIDIPVPKYL591SSVSSQET
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 95 | Prediction (Low) | - | - |
| 229 | Prediction (Medium) | - | - |
| 462 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 66 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 107 | Y → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 149 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 200 | Y → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 276 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |
| 323 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |