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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PG35 MCCC1 Methylcrotonyl-CoA carboxylase subunit 1 Homo sapiens (Human) 598 aa

Protein Details: E9PG35 (MCCC1)

Protein Information
AccessionE9PG35
Protein NamesMethylcrotonyl-CoA carboxylase subunit 1
Gene SymbolMCCC1
OrganismHomo sapiens (Human)
Length598 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAASAVSVL11LVAAERNRWH21RLPSLLLPPR31TWVWRQRTMK41YTTATDEAYS
51-10051IGPAPSQQSY61LSMEKIIQVA71KTSAAQAIHP81GCGFLSENME91FAELCKQEGI
101-150101IFIGPPPSAI111RDMGIKSTSK121SIMAAAGVPV131VEGYHGEDQS141DQCLKEHARR
151-200151IGYPVMIKAV161RGGGGKGMRI171VRSEQEFQEQ181LESARREAKK191SFNDDAMLIE
201-250201KFVDTPRHVE211VQVFGDHHGN221AVYLFERDCS231VQRRHQKIIE241EAPAPGIKSE
251-300251VRKKLGEAAV261RAAKAVNYVG271AGTVEFIMDS281KHNFCFMEMN291TRLQVEHPVT
301-350301EMITGTDLVE311WQLRIAAGEK321IPLSQEEITL331QGHAFEARIY341AEDPSNNFMP
351-400351VAGPLVHLST361PRADPSTRIE371TGVRQGDEVS381VHYDPMIAKL391VVWAADRQAA
401-450401LTKLRYSLRQ411YNIVGLHTNI421DFLLNLSGHP431EFEAGNVHTD441FIPQHHKQLL
451-500451LSRKAAAKES461LCQAALGLIL471KEKAMTDTFT481LQAHDQFSPF491SSSSGRRLNI
501-550501SYTRNMTLKD511GKNNVAIAVT521YNHDGSYSMQ531IEDKTFQVLG541NLYSEGDCTY
551-598551LKCSVNGVAS561KAKLIILENT571IYLFSKEGSI581EIDIPVPKYL591SSVSSQET
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
82 - - -
Deep-Palm: 0.92
95 - - -
GPS-Palm: 0.65
Deep-Palm: 0.89
143 - - -
Deep-Palm: 0.89
229 - - -
GPS-Palm: 0.83
Deep-Palm: 0.59
285 - - -
Deep-Palm: 0.35
462 SWISSPALM DBPTM CYSMODDB - - -
GPS-Palm: 0.96
Deep-Palm: 0.98
548 - - -
Deep-Palm: 0.80
553 - - -
Deep-Palm: 0.90
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
66 R → C 0.001887 SNP Missense Mutation UCEC
107 Y → C 0.005435 SNP Missense Mutation ESCA
149 F → C 0.001887 SNP Missense Mutation UCEC
200 Y → C 0.003559 SNP Missense Mutation KIRP
276 C → F 0.001764 SNP Missense Mutation LUAD
323 F → C 0.001887 SNP Missense Mutation UCEC