Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PG39 | AGK | Acylglycerol kinase, mitochondrial (EC 2.7.1.107) … | Homo sapiens (Human) | 244 aa |
Protein Details: E9PG39 (AGK)
Protein Information
| Accession | E9PG39 |
|---|---|
| Protein Names | Acylglycerol kinase, mitochondrial (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) |
| Gene Symbol | AGK |
| Organism | Homo sapiens (Human) |
| Length | 244 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26876311 31251020 32944167 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTVFFKTLRN11HWKKTTAGLC21LLTWGGHWLY31GKHCDNLLRR41AACQEAQVFG
51-10051NQLIPPNAQV61KKATVFLNPA71ACKGTLFEKN81AAPILHLSGM91DVTIVKTDYE
101-150101GQAKKLLELM111ENTDVIIVAG121GDGTLQEVVT131GVLRRTDEAT141FSKIPIGFIP
151-200151LGETSSLSHT161LFAESGNKVQ171HITDATLAIV181KGETVPLDVL191QIKGEKEQPV
201-244201FAMTGLRWGS211FRDAGVKVSK221YWYLGPLKIK231AAHFFSTLKP241FPKR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 20 | - | - | - |
Deep-Palm: 0.71
|
|
| 34 | - | - | - |
Deep-Palm: 0.82
|
|
| 43 | - | - | - |
Deep-Palm: 0.61
|
|
| 72 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
1
frontal cortex
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 197 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 224 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 244 | W → C | 0.004219 | SNP | Missense Mutation | SARC |
| 365 | C → Y | 0.002288 | SNP | Missense Mutation | STAD |