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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PGM4 GBE1 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher … Homo sapiens (Human) 661 aa

Protein Details: E9PGM4 (GBE1)

Protein Information
AccessionE9PGM4
Protein Names1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)
Gene SymbolGBE1
OrganismHomo sapiens (Human)
Length661 aa
IsoformsNo isoforms
Related PMIDs 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MNLAKVRYKQ11FSQILKNIGE21NEGGIDKFSR31GYESFGVHRC41ADGGLYCKEW
51-10051APGAEGVFLT61GDFNGWNPFS71YPYKKLDYGK81WELYIPPKQN91KSVLVPHGSK
101-150101LKVVITSKSG111EILYRISPWA121KYVVREGDNV131NYDWIHWDPE141HSYEFKHSRP
151-200151KKPRSLRIYE161SHVGISSHEG171KVASYKHFTC181NVLPRIKGLG191YNCIQLMAIM
201-250201EHAYYASFGY211QITSFFAASS221RYGTPEELQE231LVDTAHSMGI241IVLLDVVHSH
251-300251ASKNSADGLN261MFDGTDSCYF271HSGPRGTHDL281WDSRLFAYSS291WEILRFLLSN
301-350301IRWWLEEYRF311DGFRFDGVTS321MLYHHHGVGQ331GFSGDYSEYF341GLQVDEDALT
351-400351YLMLANHLVH361TLCPDSITIA371EDVSGMPALC381SPISQGGGGF391DYRLAMAIPD
401-450401KWIQLLKEFK411DEDWNMGDIV421YTLTNRRYLE431KCIAYAESHD441QALVGDKSLA
451-500451FWLMDAEMYT461NMSVLTPFTP471VIDRGIQLHK481MIRLITHGLG491GEGYLNFMGN
501-550501EFGHPEWLDF511PRKGNNESYH521YARRQFHLTD531DDLLRYKFLN541NFDRDMNRLE
551-600551ERYGWLAAPQ561AYVSEKHEGN571KIIAFERAGL581LFIFNFHPSK591SYTDYRVGTA
601-650601LPGKFKIVLD611SDAAEYGGHQ621RLDHSTDFFS631EAFEHNGRPY641SLLVYIPSRV
651-661651ALILQNVDLP661N
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
40 Glycoside hydrolase, family 13, N-terminal Immunoglobulin-like fold 1,4-ALPHA-GLUCAN-BRANCHING ENZYME Immunoglobulin E-set - -
Deep-Palm: 0.69
47 Immunoglobulin-like fold Glycoside hydrolase, family 13, N-terminal 1,4-ALPHA-GLUCAN-BRANCHING ENZYME Immunoglobulin E-set - -
Deep-Palm: 0.50
180 - - -
GPS-Palm: 0.89
Deep-Palm: 0.90
193 - - -
GPS-Palm: 0.72
Deep-Palm: 0.17
268 - - -
Deep-Palm: 0.11
363 - - -
Deep-Palm: 0.92
380 - - -
GPS-Palm: 0.72
Deep-Palm: 0.88
432 - - -
Deep-Palm: 0.89
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
PC3
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
72 G → C 0.003460 SNP Missense Mutation CESC
114 Y → C 0.001764 SNP Missense Mutation LUAD
156 R → C 0.002141 SNP Missense Mutation SKCM
166 R → C 0.002141 SNP Missense Mutation SKCM
202 S → C 0.001014 SNP Missense Mutation BRCA
355 R → C 0.002506 SNP Missense Mutation COAD
355 R → C 0.002141 SNP Missense Mutation SKCM
576 R → C 0.004283 SNP Missense Mutation SKCM
679 R → C 0.002288 SNP Missense Mutation STAD