Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PIE4 | MTCH2 | Mitochondrial carrier homolog 2 | Homo sapiens (Human) | 294 aa |
Protein Details: E9PIE4 (MTCH2)
Protein Information
| Accession | E9PIE4 |
|---|---|
| Protein Names | Mitochondrial carrier homolog 2 |
| Gene Symbol | MTCH2 |
| Organism | Homo sapiens (Human) |
| Length | 294 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.650
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.650
13/46 (28.3%)
4
Cerebral cortex
Specificity: 0.200
4/4 (100.0%)
3
PC3 cells
Specificity: 0.150
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADAASQVLL11GSGLTILSQP21LMYVKVLIQV31GYEPLPPTIG41RNIFGRQVCQ
51-10051LPGLFSYAQH61IASIDGRRGL71FTGLTPRLCS81GVLGTVVHGK91VLQELGPGNV
101-150101QKEVSSSFDH111VIKETTREMI121ARSAATLITH131PFHVITLRSM141VQFIGRESKY
151-200151CGLCDSIITI161YREEGILGFF171AGLVPRLLGD181ILSLWLCNSL191AYLVNTYALD
201-250201SGVSTMNEMK211SYSQAVTGFF221ASMLTYPFVL231VSNLMAVNNC241GLAGGCPPYS
251-294251PIYTSWIDCW261CMLQKEGNMS271RGNSLFFRKV281PFGKTYCCDL291KMLI
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 49 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | - |
| 79 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 151 | Prediction (Medium) | - | - |
| 154 | Prediction (High) | - | - |
| 187 | Prediction (Medium) | - | - |
| 287 | Prediction (High) | - | - |
| 288 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 49 | C → R | 0.001969 | SNP | Missense Mutation | HNSC |
| 57 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 60 | H → delinsLSGFFCYALN | 0.002506 | INS | In Frame Ins | COAD |
| 62 | A → Cfs*29 | 0.003460 | INS | Frame Shift Ins | CESC |
| 68 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 131 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 160 | C → R | 0.002976 | SNP | Missense Mutation | KIRC |
| 170 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 185 | R → C | 0.003460 | SNP | Missense Mutation | CESC |