Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PIF1 | CD81 | CD81 antigen | Homo sapiens (Human) | 242 aa |
Protein Details: E9PIF1 (CD81)
Protein Information
| Accession | E9PIF1 |
|---|---|
| Protein Names | CD81 antigen |
| Gene Symbol | CD81 |
| Organism | Homo sapiens (Human) |
| Length | 242 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEEVTEAQKT11HQARLGCEVP21CCSSLAVSNP31TSSQLGGPWW41VRHPGPSGVL
51-10051GCGECVGTHL61VSLSPQGIYI71LIAVGAVMMF81VGFLGCYGAI91QESQCLLGTF
101-150101FTCLVILFAC111EVAAGIWGFV121NKDQIAKDVK131QFYDQALQQA141VVDDDANNAK
151-200151AVVKTFHETL161DCCGSSTLTA171LTTSVLKNNL181CPSGSNIISN191LFKEDCHQKI
201-242201DDLFSGKLYL211IGIAAIVVAV221IMIFEMILSM231VLCCGIRNSS241VY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.87
|
|
| 21 | - | - | - |
Deep-Palm: 0.84
|
|
| 22 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.87
|
|
| 52 | - | - | - |
Deep-Palm: 0.87
|
|
| 55 | - | - | - |
Deep-Palm: 0.86
|
|
| 86 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.95
|
|
| 95 | - | - | - |
Deep-Palm: 0.89
|
|
| 103 | - | - | - |
Deep-Palm: 0.94
|
|
| 110 | - | - | - |
Deep-Palm: 0.38
|
|
| 162 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.82
Deep-Palm: 0.95
|
| 163 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.90
Deep-Palm: 0.92
|
| 181 | - |
HeLa
(29575903)
|
cerebral cortex
(36430497)
LNCaP
(31251020)
|
GPS-Palm: 0.75
Deep-Palm: 0.88
|
|
| 196 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.65
Deep-Palm: 0.36
|
|
| 233 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.03
|
|
| 234 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
3
LNCaP
Specificity: 0.214
3/3 (100.0%)
1
DU145 cell
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Cerebral Cortex (Mass)
Specificity: 0.286
4/4 (100.0%)
2
LNCaP cells (Mass)
Specificity: 0.143
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 157 | C → F | 0.003559 | SNP | Missense Mutation | KIRP |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |