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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PIN3 NXF1 Nuclear RNA export factor 1 Homo sapiens (Human) 603 aa

Protein Details: E9PIN3 (NXF1)

Protein Information
Accession E9PIN3
Protein Names Nuclear RNA export factor 1
Gene Symbol NXF1
Organism Homo sapiens (Human)
Length 603 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.944
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.944
34/46 (73.9%)
2
PC3 cells
Specificity: 0.056
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADEGKSYSV11STSFFKSPTQ21FSSNFSLMLP31SHREGSFLWI41GSGVCMEMAS
51-10051VVKHDDERVN61FPQRKKKGRG71PFRWKYGEGN81RRSGRGGSGI91RSSRLEEDDG
101-150101DVAMSDAQDG111PRVRYNPYTT121RPNRRGDTWH131DRDRIHVTVR141RDRAPPERGG
151-200151AGTSQDGTSK161NWFKITIPYG171RKYDKAWLLS181MIQSKCSVPF191TPIEFHYENT
201-250201RAQFFVEDAS211TASALKAVNY221KILDRENRRI231SIIINSSAPP241HTILNELKPE
251-300251QVEQLKLIMS261KRYDGSQQAL271DLKGLRSDPD281LVAQNIDVVL291NRRSCMAATL
301-350301RIIEENIPEL311LSLNLSNNRL321YRLDDMSSIV331QKAPNLKILN341LSGNELKSER
351-400351ELDKIKGLKL361EELWLDGNSL371CDTFRDQSTY381ISAIRERFPK391LLRLDGHELP
401-450401PPIAFDVEAP411TTLPPCKGSY421FGTENLKSLV431LHFLQQYYAI441YDSGDRQGLL
451-500451DAYHDGACCS461LSIPFIPQNP471ARSSLAEYFK481DSRNVKKLKD491PTLRFRLLKH
501-550501TRLNVVAFLN511ELPKTQHDVN521SFVVDISAQT531STLLCFSVNG541VFKEVDGKSR
551-600551DSLRAFTRTF561IAVPASNSGL571CIVNDELFVR581NASSEEIQRA591FAMPAPTPSS
601-603601SPV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
45 Prediction (Low) - -
295 Prediction (High) - -
459 Prediction (Low) - -
571 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) Nuclear RNA export factor NTF2 domain 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
15 R → C 0.001887 SNP Missense Mutation UCEC
177 Y → C 0.002506 SNP Missense Mutation COAD
223 S → C 0.001014 SNP Missense Mutation BRCA
233 R → C 0.002288 SNP Missense Mutation STAD
299 S → C 0.002033 SNP Missense Mutation LUSC
342 R → C 0.002141 SNP Missense Mutation SKCM
459 R → C 0.001887 SNP Missense Mutation UCEC
459 R → C 0.003460 SNP Missense Mutation CESC
492 C → G 0.006993 SNP Missense Mutation LAML
494 S → Cfs*29 0.002506 DEL Frame Shift Del COAD