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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PIN3 NXF1 Nuclear RNA export factor 1 Homo sapiens (Human) 603 aa

Protein Details: E9PIN3 (NXF1)

Protein Information
AccessionE9PIN3
Protein NamesNuclear RNA export factor 1
Gene SymbolNXF1
OrganismHomo sapiens (Human)
Length603 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MADEGKSYSV11STSFFKSPTQ21FSSNFSLMLP31SHREGSFLWI41GSGVCMEMAS
51-10051VVKHDDERVN61FPQRKKKGRG71PFRWKYGEGN81RRSGRGGSGI91RSSRLEEDDG
101-150101DVAMSDAQDG111PRVRYNPYTT121RPNRRGDTWH131DRDRIHVTVR141RDRAPPERGG
151-200151AGTSQDGTSK161NWFKITIPYG171RKYDKAWLLS181MIQSKCSVPF191TPIEFHYENT
201-250201RAQFFVEDAS211TASALKAVNY221KILDRENRRI231SIIINSSAPP241HTILNELKPE
251-300251QVEQLKLIMS261KRYDGSQQAL271DLKGLRSDPD281LVAQNIDVVL291NRRSCMAATL
301-350301RIIEENIPEL311LSLNLSNNRL321YRLDDMSSIV331QKAPNLKILN341LSGNELKSER
351-400351ELDKIKGLKL361EELWLDGNSL371CDTFRDQSTY381ISAIRERFPK391LLRLDGHELP
401-450401PPIAFDVEAP411TTLPPCKGSY421FGTENLKSLV431LHFLQQYYAI441YDSGDRQGLL
451-500451DAYHDGACCS461LSIPFIPQNP471ARSSLAEYFK481DSRNVKKLKD491PTLRFRLLKH
501-550501TRLNVVAFLN511ELPKTQHDVN521SFVVDISAQT531STLLCFSVNG541VFKEVDGKSR
551-600551DSLRAFTRTF561IAVPASNSGL571CIVNDELFVR581NASSEEIQRA591FAMPAPTPSS
601-603601SPV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
45 - - -
GPS-Palm: 0.67
Deep-Palm: 0.53
186 - - -
Deep-Palm: 0.18
295 - - -
GPS-Palm: 0.92
Deep-Palm: 0.87
371 - - -
Deep-Palm: 0.91
416 - - -
Deep-Palm: 0.83
458 - - -
Deep-Palm: 0.96
459 - - -
GPS-Palm: 0.72
Deep-Palm: 0.95
535 - - -
Deep-Palm: 0.49
571 SWISSPALM DBPTM CYSMODDB Nuclear RNA export factor NTF2 domain - -
GPS-Palm: 0.86
Deep-Palm: 0.80
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
LNCaP
Specificity: 0.600
3/3 (100.0%)
2
PC3
Specificity: 0.400
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
15 R → C 0.001887 SNP Missense Mutation UCEC
177 Y → C 0.002506 SNP Missense Mutation COAD
223 S → C 0.001014 SNP Missense Mutation BRCA
233 R → C 0.002288 SNP Missense Mutation STAD
299 S → C 0.002033 SNP Missense Mutation LUSC
342 R → C 0.002141 SNP Missense Mutation SKCM
459 R → C 0.001887 SNP Missense Mutation UCEC
459 R → C 0.003460 SNP Missense Mutation CESC
492 C → G 0.006993 SNP Missense Mutation LAML
494 S → Cfs*29 0.002506 DEL Frame Shift Del COAD