Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PK25 CFL1 Cofilin 1 Homo sapiens (Human) 204 aa

Protein Details: E9PK25 (CFL1)

Protein Information
Accession E9PK25
Protein Names Cofilin 1
Gene Symbol CFL1
Organism Homo sapiens (Human)
Length 204 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.921
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.921
35/46 (76.1%)
3
PC3 cells
Specificity: 0.079
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVSPGHGHLR11ERKELTPHST21NPAAARIWDA31TYSDGYVRPA41SGVAVSDGVI
51-10051KVFNDMKVRK61SSTPEEVKKR71KKAVLFCLSE81DKKNIILEEG91KEILVGDVGQ
101-150101TVDDPYATFV111KMLPDKDCRY121ALYDATYETK131ESKKEDLVFI141FWAPESAPLK
151-200151SKMIYASSKD161AIKKKLTGIK171HELQANCYEE181VKDRCTLAEK191LGGSAVISLE
201-204201GKPL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
77 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
32 R → C 0.001887 SNP Missense Mutation UCEC
80 C → C 0.002427 SNP Silent BLCA