Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PKY0 | CTNND1 | Catenin delta 1 | Homo sapiens (Human) | 126 aa |
Protein Details: E9PKY0 (CTNND1)
Protein Information
| Accession | E9PKY0 |
|---|---|
| Protein Names | Catenin delta 1 |
| Gene Symbol | CTNND1 |
| Organism | Homo sapiens (Human) |
| Length | 126 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MIGEEVPSDQ11YYWAPLAQHE21RGSLASLDSL31RKGGPPPPNW41RQPELPEVIA
51-10051MLGFRLDAVK61SNAAAYLQHL71CYRNDKVKTD81VRKLKGIPVL91VGLLDHPKKE
101-126101VHLGACGALK111NISFGRDQDN121KIAIKN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 71 | SWISSPALM DBPTM CYSMODDB | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.84
Deep-Palm: 0.96
|
| 106 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
PC3
Specificity: 0.571
4/4 (100.0%)
2
HeLa cell
Specificity: 0.286
2/2 (100.0%)
1
LNCaP
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 280 | Y → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 290 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 450 | C → W | 0.001887 | SNP | Missense Mutation | UCEC |
| 497 | L → Cfs*13 | 0.002427 | DEL | Frame Shift Del | BLCA |
| 533 | C → C | 0.001887 | SNP | Silent | UCEC |
| 777 | S → C | 0.004219 | SNP | Missense Mutation | SARC |