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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PLK4 AHNAK AHNAK nucleoprotein Homo sapiens (Human) 144 aa

Protein Details: E9PLK4 (AHNAK)

Protein Information
AccessionE9PLK4
Protein NamesAHNAK nucleoprotein
Gene SymbolAHNAK
OrganismHomo sapiens (Human)
Length144 aa
IsoformsNo isoforms
Related PMIDs 29575903 32944167
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEKEETTREL11LLPNWQGSGS21HGLTIAQRDD31GVFVQEVTQN41SPAARTGVVK
51-10051EGDQIVGATI61YFDNLQSGEV71TQLLNTMGHH81TVGLKLHRKG91DRSPEPGQTW
101-144101TREVFSSCSS111EVVLSGDDEE121YQRIYTTKIK131PRLKSEDGVE141GDLG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
108 - - -
Deep-Palm: 0.81
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
PC3
Specificity: 0.800
4/4 (100.0%)
1
HeLa cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
19 G → Cfs*12 0.003460 INS Frame Shift Ins CESC
57 G → C 0.001764 SNP Missense Mutation LUAD
102 R → C 0.007299 SNP Missense Mutation READ
149 R → C 0.002506 SNP Missense Mutation COAD
149 R → C 0.001887 SNP Missense Mutation UCEC
673 L → Cfs*4 0.001969 DEL Frame Shift Del HNSC
679 K → Cfs*2 0.002427 DEL Frame Shift Del BLCA
728 G → C 0.001764 SNP Missense Mutation LUAD
767 P → Cfs*7 0.002294 DEL Frame Shift Del OV
793 S → C 0.002545 SNP Missense Mutation GBM
870 G → C 0.001887 SNP Missense Mutation UCEC
895 P → Cfs*7 0.002294 DEL Frame Shift Del OV
1088 S → C 0.002288 SNP Missense Mutation STAD
1664 G → C 0.001887 SNP Missense Mutation UCEC
2000 G → C 0.001014 SNP Missense Mutation BRCA
3022 M → Cfs*4 0.003774 DEL Frame Shift Del UCEC
3076 G → C 0.001969 SNP Missense Mutation LGG
3278 G → C 0.001887 SNP Missense Mutation UCEC
3294 S → C 0.002033 SNP Missense Mutation LUSC
4065 M → Cfs*48 0.001887 DEL Frame Shift Del UCEC
4188 M → Cfs*4 0.001014 DEL Frame Shift Del BRCA
4188 M → Cfs*4 0.001887 DEL Frame Shift Del UCEC
4278 S → C 0.003460 SNP Missense Mutation CESC
4312 W → C 0.002033 SNP Missense Mutation LUSC
4401 G → C 0.001887 SNP Missense Mutation UCEC
4594 S → C 0.002427 SNP Missense Mutation BLCA
4797 G → C 0.001764 SNP Missense Mutation LUAD
5125 S → C 0.002294 SNP Missense Mutation OV
5188 G → C 0.002545 SNP Missense Mutation GBM
5604 S → C 0.002427 SNP Missense Mutation BLCA
5613 F → C 0.005618 SNP Missense Mutation PAAD
5737 S → C 0.002545 SNP Missense Mutation GBM
5846 G → C 0.001969 SNP Missense Mutation HNSC