Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PMR4 | CD151 | Tetraspanin | Homo sapiens (Human) | 251 aa |
Protein Details: E9PMR4 (CD151)
Protein Information
| Accession | E9PMR4 |
|---|---|
| Protein Names | Tetraspanin |
| Gene Symbol | CD151 |
| Organism | Homo sapiens (Human) |
| Length | 251 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGEFNEKKTT11CGTVCLKYLL21FTYNCCFWLA31GLAVMAVGIW41TLALKSDYIS
51-10051LLASGTYLAT61AYILVVAGTV71VMVTGVLGCC81ATFKERRNLL91RLYFILLLII
101-150101FLLEIIAGIL111AYAYYQQLNT121ELKENLKDTM131TKRYHQPGHE141AVTSAVDQLQ
151-200151QEFHCCGSNN161SQDWRDSEWI171RSQEAGGRVV181PDSCCKTVVA191LCGQRDHASN
201-250201IYKGGCITKL211ETFIQEHLRV221IGAVGIGIAC231VQVFGMIFTC241CLYRSLKLEH
251-251251Y
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 11 | - | - | - |
GPS-Palm: 0.81
Deep-Palm: 0.02
|
|
| 15 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.10
|
|
| 25 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.61
|
|
| 26 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.56
|
|
| 79 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
|
| 80 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
|
| 155 | - | - | - |
Deep-Palm: 0.62
|
|
| 156 | - | - | - |
Deep-Palm: 0.57
|
|
| 184 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.84
|
| 185 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.88
|
| 192 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.80
Deep-Palm: 0.61
|
| 206 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.81
|
|
| 230 | - | - | - |
Deep-Palm: 0.69
|
|
| 240 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.04
|
|
| 241 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 0.750
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.250
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 112 | Y → C | 0.003559 | SNP | Missense Mutation | KIRP |
| 184 | C → Y | 0.002033 | SNP | Missense Mutation | LUSC |
| 232 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |