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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PN25 HSPA8 Heat shock protein family A … Homo sapiens (Human) 132 aa

Protein Details: E9PN25 (HSPA8)

Protein Information
Accession E9PN25
Protein Names Heat shock protein family A (Hsp70) member 8
Gene Symbol HSPA8
Organism Homo sapiens (Human)
Length 132 aa
Isoforms No isoforms
Related PMIDs 21076176 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.783
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.783
36/46 (78.3%)
6
Jurkat T cells
Specificity: 0.130
6/25 (24.0%)
4
PC3 cells
Specificity: 0.087
4/4 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSKGPAVGID11LGTTYSCVGV21FQHGKVEIIA31NDQGNRTTPS41YVAFTDTERL
51-10051IGDAAKNQVA61MNPTNTVFDA71KRLIGRRFDD81AVVQSDMKHW91PFMVVNDAGR
101-132101PKVQVEYKGE111TKSFYPEEVS121SMVLTKMKEI131AE
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
17 CYSMODDB SWISSPALM DBPTM Hsp70 protein -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
267 C → W 0.002020 SNP Missense Mutation PRAD
311 R → C 0.001969 SNP Missense Mutation HNSC
342 R → C 0.001887 SNP Missense Mutation UCEC
416 R → C 0.001887 SNP Missense Mutation UCEC
580 W → C 0.002033 SNP Missense Mutation LUSC