Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PN99 ECE1 Endothelin converting enzyme 1 Homo sapiens (Human) 103 aa

Protein Details: E9PN99 (ECE1)

Protein Information
AccessionE9PN99
Protein NamesEndothelin converting enzyme 1
Gene SymbolECE1
OrganismHomo sapiens (Human)
Length103 aa
IsoformsNo isoforms
Related PMIDs 29575903 31251020 32944167
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSTYKRATLD11EEDLVDSLSE21GDAYPNGLQV31NFHSPRSGQR41CWAARTQVEK
51-10051RLVVLVVLLA61AGLVACLAAL71GIQYQTRSPS81VCLSEACVSV91TSSILSSMDP
101-103101TVD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 SWISSPALM DBPTM CYSMODDB -
HeLa (29575903)
-
GPS-Palm: 0.72
Deep-Palm: 0.95
66 - - -
GPS-Palm: 0.86
Deep-Palm: 0.98
82 - - -
Deep-Palm: 0.90
87 - - -
Deep-Palm: 0.74
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
PC3
Specificity: 0.500
4/4 (100.0%)
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
1
HeLa cell
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
83 C → Y 0.002288 SNP Missense Mutation STAD
83 C → F 0.002141 SNP Missense Mutation SKCM
104 C → C 0.002288 SNP Silent STAD
183 R → C 0.001887 SNP Missense Mutation UCEC
208 G → C 0.002506 SNP Missense Mutation COAD
232 R → C 0.002506 SNP Missense Mutation COAD
409 R → C 0.002141 SNP Missense Mutation SKCM
509 F → C 0.002141 SNP Missense Mutation SKCM
630 W → C 0.002427 SNP Missense Mutation BLCA
736 R → C 0.002141 SNP Missense Mutation SKCM
767 C → C 0.002506 SNP Silent COAD