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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PN99 ECE1 Endothelin converting enzyme 1 Homo sapiens (Human) 103 aa

Protein Details: E9PN99 (ECE1)

Protein Information
Accession E9PN99
Protein Names Endothelin converting enzyme 1
Gene Symbol ECE1
Organism Homo sapiens (Human)
Length 103 aa
Isoforms No isoforms
Related PMIDs 19801377 29575903 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.837
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.837
36/46 (78.3%)
4
PC3 cells
Specificity: 0.093
4/4 (100.0%)
2
DU145 cells
Specificity: 0.047
2/2 (100.0%)
1
HeLa cells
Specificity: 0.023
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSTYKRATLD11EEDLVDSLSE21GDAYPNGLQV31NFHSPRSGQR41CWAARTQVEK
51-10051RLVVLVVLLA61AGLVACLAAL71GIQYQTRSPS81VCLSEACVSV91TSSILSSMDP
101-103101TVD
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
41 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Low) - 29575903
66 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
83 C → Y 0.002288 SNP Missense Mutation STAD
83 C → F 0.002141 SNP Missense Mutation SKCM
104 C → C 0.002288 SNP Silent STAD
183 R → C 0.001887 SNP Missense Mutation UCEC
208 G → C 0.002506 SNP Missense Mutation COAD
232 R → C 0.002506 SNP Missense Mutation COAD
409 R → C 0.002141 SNP Missense Mutation SKCM
509 F → C 0.002141 SNP Missense Mutation SKCM
630 W → C 0.002427 SNP Missense Mutation BLCA
736 R → C 0.002141 SNP Missense Mutation SKCM
767 C → C 0.002506 SNP Silent COAD