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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
E9PNG1 TMEM63B Transmembrane protein 63B Homo sapiens (Human) 226 aa

Protein Details: E9PNG1 (TMEM63B)

Protein Information
Accession E9PNG1
Protein Names Transmembrane protein 63B
Gene Symbol TMEM63B
Organism Homo sapiens (Human)
Length 226 aa
Isoforms No isoforms
Related PMIDs 19801377 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.848
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
28
LNCaP cells
Specificity: 0.848
28/46 (60.9%)
3
PC3 cells
Specificity: 0.091
3/4 (75.0%)
2
DU145 cells
Specificity: 0.061
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MLPFLLATLG11TTALNNSNPK21DYCYSARIRS31TVLQGLPFGG41VPTVLALDFM
51-10051CFLALLFLFS61ILRKVAWDYG71RLALVTDADR81LRRQERDRVE91QEYVASAMHG
101-150101DSHDRYERLT111SVSSSVDFDQ121RDNGFCSWLT131AIFRIKDDEI141RDKCGGDAVH
151-200151YLSFQRHIIG161LLVVVGVLSV171GIVLPVNFSG181DLLENNAYSF191GRTTIANLKS
201-226201GNNLLWLHTS211FAFLYLLLTV221YSMRRH
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
23 Prediction (Low) - -
126 CYSMODDB SWISSPALM DBPTM Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
108 R → C 0.001887 SNP Missense Mutation UCEC
128 W → C 0.001764 SNP Missense Mutation LUAD
231 R → C 0.007299 SNP Missense Mutation READ
303 S → C 0.001764 SNP Missense Mutation LUAD
394 R → C 0.003460 SNP Missense Mutation CESC
431 W → C 0.002427 SNP Missense Mutation BLCA
433 R → C 0.002020 SNP Missense Mutation PRAD
542 R → C 0.001969 SNP Missense Mutation LGG
580 G → C 0.002033 SNP Missense Mutation THCA
587 R → C 0.002747 SNP Missense Mutation LIHC
651 Y → C 0.001887 SNP Missense Mutation UCEC
702 R → C 0.002506 SNP Missense Mutation COAD
735 Y → C 0.001887 SNP Missense Mutation UCEC