Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PPI4 | SLC35C1 | Solute carrier family 35 member … | Homo sapiens (Human) | 165 aa |
Protein Details: E9PPI4 (SLC35C1)
Protein Information
| Accession | E9PPI4 |
|---|---|
| Protein Names | Solute carrier family 35 member C1 |
| Gene Symbol | SLC35C1 |
| Organism | Homo sapiens (Human) |
| Length | 165 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.926
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
25
LNCaP cells
Specificity: 0.926
25/46 (54.3%)
2
PC3 cells
Specificity: 0.074
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MALTGASDPS11AEAEANGEKP21FLLRALQIAL31VVSLYWVTSI41SMVFLNKYLL
51-10051DSPSLRLDTP61IFVTFYQCLV71TTLLCKGLSA81LAACCPGAVD91FPSLRLDLRV
101-150101ARSVLPLSVV111FIGMITFNNL121CLKYVGVAFY131NVGRSLTTVF141NVLLSYLLLK
151-165151QTTSFYALLT161CGIII
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 68 | Prediction (Low) | - | - |
| 75 | Prediction (Low) | - | - |
| 84 | CYSMODDB SWISSPALM DBPTM Prediction (Low) | - | - |
| 85 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 121 | Prediction (Medium) | - | - |
| 161 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 139 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 174 | C → C | 0.002288 | SNP | Silent | STAD |
| 174 | C → G | 0.002033 | SNP | Missense Mutation | LUSC |
| 182 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 233 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 239 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 256 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |