Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PPI4 | SLC35C1 | Solute carrier family 35 member … | Homo sapiens (Human) | 165 aa |
Protein Details: E9PPI4 (SLC35C1)
Protein Information
| Accession | E9PPI4 |
|---|---|
| Protein Names | Solute carrier family 35 member C1 |
| Gene Symbol | SLC35C1 |
| Organism | Homo sapiens (Human) |
| Length | 165 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MALTGASDPS11AEAEANGEKP21FLLRALQIAL31VVSLYWVTSI41SMVFLNKYLL
51-10051DSPSLRLDTP61IFVTFYQCLV71TTLLCKGLSA81LAACCPGAVD91FPSLRLDLRV
101-150101ARSVLPLSVV111FIGMITFNNL121CLKYVGVAFY131NVGRSLTTVF141NVLLSYLLLK
151-165151QTTSFYALLT161CGIII
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 68 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.97
|
|
| 75 | - | - | - |
GPS-Palm: 0.70
Deep-Palm: 0.90
|
|
| 84 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.77
Deep-Palm: 0.98
|
| 85 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.92
Deep-Palm: 0.98
|
| 121 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.30
|
|
| 161 | - | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
3
LNCaP
Specificity: 0.500
3/3 (100.0%)
2
PC3
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.167
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 139 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 174 | C → C | 0.002288 | SNP | Silent | STAD |
| 174 | C → G | 0.002033 | SNP | Missense Mutation | LUSC |
| 182 | W → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 233 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 239 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 256 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |