Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| E9PS44 | IFITM3 | Interferon induced transmembrane protein 3 | Homo sapiens (Human) | 112 aa |
Protein Details: E9PS44 (IFITM3)
Protein Information
| Accession | E9PS44 |
|---|---|
| Protein Names | Interferon induced transmembrane protein 3 |
| Gene Symbol | IFITM3 |
| Organism | Homo sapiens (Human) |
| Length | 112 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLKEEHEVAV11LGAPHNPAPP21TSTVIHIRSE31TSVPDHVVWS41LFNTLFMNPC
51-10051CLGFIAFAYS61VKSRDRKMVG71DVTGAQAYAS81TAKCLNIWAL91ILGILMTILL
101-112101IVIPVLIFQA111YG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 50 | SWISSPALM DBPTM CYSMODDB | Interferon-induced transmembrane protein CD225/Dispanin family Interferon-induced transmembrane antiviral protein |
HeLa
(29575903)
| - |
GPS-Palm: 0.86
Deep-Palm: 0.70
|
| 51 | SWISSPALM DBPTM CYSMODDB | Interferon-induced transmembrane protein CD225/Dispanin family Interferon-induced transmembrane antiviral protein |
HeLa
(29575903)
| - |
GPS-Palm: 0.89
Deep-Palm: 0.74
|
| 84 | - | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
PC3
Specificity: 0.667
4/4 (100.0%)
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 71 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |