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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F5GWI0 DDB1 Damage specific DNA binding protein … Homo sapiens (Human) 370 aa

Protein Details: F5GWI0 (DDB1)

Protein Information
Accession F5GWI0
Protein Names Damage specific DNA binding protein 1
Gene Symbol DDB1
Organism Homo sapiens (Human)
Length 370 aa
Isoforms No isoforms
Related PMIDs 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
4
PC3 cells
Specificity: 0.143
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MYGKIAVMEL11FRPKGESKDL21LFILTAKYNA31CILEYKQSGE41SIDIITRAHG
51-10051NVQDRIGRPS61ETGIIGIIDP71ECRMIGLRLY81DGLFKVIPLD91RDNKELKAFN
101-150101IRLEELHVID111VKFLYGCQAP121TICFVYQDPQ131GRHVKTYEVS141LREKEFNKGP
151-200151WKQENVEAEA161SMVIAVPEPF171GGAIIIGQES181ITYHNGDKYL191AIAPPIIKQS
201-250201TIVCHNRVDP211NGSRYLLGDM221EGRLFMLLLE231KEEQMDGTVT241LKDLRVELLG
251-300251ETSIAECLTY261LDNGVVFVGS271RLGDSQLVKL281NVDSNEQGSY291VVAMETFTNL
301-350301GPIVDMCVVD311LERQGQGQLV321TCSGAFKEGS331LRIIRNGIGI341HEHASIDLPG
351-370351IKDHFSIGEV361GLSRTQSSGQ
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
31 Prediction (High) - -
72 CYSMODDB SWISSPALM DBPTM RSE1/DDB1/CPSF1 first beta-propeller -
117 Prediction (Medium) - -
322 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
147 R → C 0.001887 SNP Missense Mutation UCEC
158 R → C 0.002506 SNP Missense Mutation COAD
182 Y → C 0.002288 SNP Missense Mutation STAD
313 C → C 0.001887 SNP Silent UCEC
323 F → C 0.007299 SNP Missense Mutation READ
327 R → C 0.001969 SNP Missense Mutation HNSC
327 R → C 0.002141 SNP Missense Mutation SKCM
613 Y → C 0.002141 SNP Missense Mutation SKCM
642 R → C 0.002141 SNP Missense Mutation SKCM
655 R → C 0.001014 SNP Missense Mutation BRCA
713 R → C 0.004283 SNP Missense Mutation SKCM
713 R → C 0.001887 SNP Missense Mutation UCEC
819 C → C 0.002141 SNP Silent SKCM
928 R → C 0.002288 SNP Missense Mutation STAD
928 R → C 0.001887 SNP Missense Mutation UCEC
1047 W → Cfs*15 0.002976 INS Frame Shift Ins KIRC