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UniProt ID Gene Symbol Protein Name Organism Length Action
F5GWU4 AP3B2 Adaptor related protein complex 3 … Homo sapiens (Human) 193 aa

Protein Details: F5GWU4 (AP3B2)

Protein Information
AccessionF5GWU4
Protein NamesAdaptor related protein complex 3 subunit beta 2
Gene SymbolAP3B2
OrganismHomo sapiens (Human)
Length193 aa
IsoformsNo isoforms
Related PMIDs 26876311
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLDTNKDSLK11LEAMKRIVAM21IARGKNASDL31FPAVVKNVAC41KNIEVKKLVY
51-10051VYLVRYAEEQ61QDLALLSIST71FQRGLKDPNQ81LIRASALRVL91SSIRVPIIVP
101-150101IMMLAIKEAA111SDMSPYVRKT121AAHAIPKLYS131LDSDQKDQLI141EVIEKLLADK
151-193151TTLVAGSVVM161AFEEVCPERI171DLIHKNYRKL181CNLLIDVEEW191GQV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
40 Clathrin/coatomer adaptor, adaptin-like, N-terminal Armadillo-like helical Armadillo-type fold AP complex subunit beta - -
GPS-Palm: 0.84
Deep-Palm: 0.96
166 - - -
GPS-Palm: 0.87
Deep-Palm: 0.74
181 - - -
GPS-Palm: 0.68
Deep-Palm: 0.14
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
frontal cortex
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
100 Y → C 0.002747 SNP Missense Mutation LIHC
127 R → C 0.002506 SNP Missense Mutation COAD
127 R → C 0.004283 SNP Missense Mutation SKCM
132 R → C 0.002288 SNP Missense Mutation STAD
435 R → C 0.007299 SNP Missense Mutation READ
444 R → C 0.002506 SNP Missense Mutation COAD
444 R → C 0.002141 SNP Missense Mutation SKCM
576 R → C 0.003774 SNP Missense Mutation UCEC
580 R → C 0.002506 SNP Missense Mutation COAD
654 R → C 0.002427 SNP Missense Mutation BLCA
654 R → C 0.001887 SNP Missense Mutation UCEC
707 S → C 0.002506 SNP Missense Mutation COAD
710 G → C 0.001764 SNP Missense Mutation LUAD
844 S → C 0.002427 SNP Missense Mutation BLCA
954 C → C 0.002294 SNP Splice Region OV
1026 C → Y 0.002747 SNP Missense Mutation LIHC