Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F5GXU9 | BCKDHA | 2-oxoisovalerate dehydrogenase subunit alpha (EC … | Homo sapiens (Human) | 328 aa |
Protein Details: F5GXU9 (BCKDHA)
Protein Information
| Accession | F5GXU9 |
|---|---|
| Protein Names | 2-oxoisovalerate dehydrogenase subunit alpha (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) |
| Gene Symbol | BCKDHA |
| Organism | Homo sapiens (Human) |
| Length | 328 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
26
LNCaP cells
Specificity: 1.000
26/46 (56.5%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAVAIAAARV11WRLNRGLSQA21ALLLLRQPGA31RGLARSHPPR41QQQQFSSLDD
51-10051KPQFPGASAE61FIDKLEFIQP71NVISGIPIYR81VMDRQGQIIN91PSEDPHGRIS
101-150101FYMTNYGEEG111THVGSAAALD121NTDLVFGQYR131EAGVLMYRDY141PLELFMAQCY
151-200151GNISDLGKGR161QMPVHYGCKE171RHFVTISSPL181ATQIPQAVGA191AYAAKRANAN
201-250201RVVICYFGEG211AASEGDAHAG221FNFAATLECP231IIFFCRNNGY241AISTPTSEQY
251-300251RGDGIAARGP261GYGIMSIRVD271GNDVFAVYNA281TKEARRRAVA291ENQPFLIEAM
301-328301TYRIGHHSTS311DDSSAYRSVD321EVNYWDKQ
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 168 | Prediction (Low) | - | - |
| 205 | Prediction (Low) | - | - |
| 235 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 86 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 120 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 169 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 279 | Y → Cfs*34 | 0.002294 | INS | Frame Shift Ins | OV |
| 367 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |