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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F5GXY2 LDHA L-lactate dehydrogenase A chain (LDH … Homo sapiens (Human) 156 aa

Protein Details: F5GXY2 (LDHA)

Protein Information
Accession F5GXY2
Protein Names L-lactate dehydrogenase A chain (LDH muscle subunit)
Gene Symbol LDHA
Organism Homo sapiens (Human)
Length 156 aa
Isoforms No isoforms
Related PMIDs 21076176 31251020 32944167
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.750
24/46 (52.2%)
4
Jurkat T cells
Specificity: 0.125
4/25 (16.0%)
4
PC3 cells
Specificity: 0.125
4/4 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MATLKDQLIY11NLLKEEQTPQ21NKITVVGVGA31VGMACAISIL41MKDLADELAL
51-10051VDVIEDKLKG61EMMDLQHGSL71FLRTPKIVSG81KDYNVTANSK91LVIITAGARQ
101-150101QEGESRLNLV111QRNVNIFKFI121IPNVVKYSPN131CKLLIVSNPV141DILTYVAWKI
151-156151SGFPKN
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
35 Prediction (Medium) - -
131 CYSMODDB SWISSPALM DBPTM lactate/malate dehydrogenase NAD binding domain -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
99 R → C 0.003460 SNP Missense Mutation CESC
106 R → C 0.001969 SNP Missense Mutation HNSC
157 R → C 0.002288 SNP Missense Mutation STAD
171 R → C 0.002141 SNP Missense Mutation SKCM