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UniProt ID Gene Symbol Protein Name Organism Length Action
F5GZY8 DDB1 Damage specific DNA binding protein … Homo sapiens (Human) 146 aa

Protein Details: F5GZY8 (DDB1)

Protein Information
AccessionF5GZY8
Protein NamesDamage specific DNA binding protein 1
Gene SymbolDDB1
OrganismHomo sapiens (Human)
Length146 aa
IsoformsNo isoforms
Related PMIDs 31251020 32944167 36430497
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSYNYVVTAQ11KPTAVNGCVT21GHFTSAEDLN31LLIAKNTRLE41IYVVTAEGLR
51-10051PVKEVGMYGK61IAVMELFRPK71GESKDLLFIL81TAKYNACILE91YKQSGESIDI
101-146101ITRAHGNVQD111RIGRPSETGI121IGIIDPECRM131IGLRLYDGLF141KVIPLD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
18 WD40/YVTN repeat-like-containing domain superfamily - -
Deep-Palm: 0.89
87 - - -
GPS-Palm: 0.91
Deep-Palm: 0.74
128 SWISSPALM DBPTM CYSMODDB RSE1/DDB1/CPSF1 first beta-propeller -
cerebral cortex (36430497)
Unknown (32651440)
Deep-Palm: 0.92
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
147 R → C 0.001887 SNP Missense Mutation UCEC
158 R → C 0.002506 SNP Missense Mutation COAD
182 Y → C 0.002288 SNP Missense Mutation STAD
313 C → C 0.001887 SNP Silent UCEC
323 F → C 0.007299 SNP Missense Mutation READ
327 R → C 0.001969 SNP Missense Mutation HNSC
327 R → C 0.002141 SNP Missense Mutation SKCM
613 Y → C 0.002141 SNP Missense Mutation SKCM
642 R → C 0.002141 SNP Missense Mutation SKCM
655 R → C 0.001014 SNP Missense Mutation BRCA
713 R → C 0.004283 SNP Missense Mutation SKCM
713 R → C 0.001887 SNP Missense Mutation UCEC
819 C → C 0.002141 SNP Silent SKCM
928 R → C 0.002288 SNP Missense Mutation STAD
928 R → C 0.001887 SNP Missense Mutation UCEC
1047 W → Cfs*15 0.002976 INS Frame Shift Ins KIRC