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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F5H245 LDHC L-lactate dehydrogenase (EC 1.1.1.27) Homo sapiens (Human) 318 aa

Protein Details: F5H245 (LDHC)

Protein Information
Accession F5H245
Protein Names L-lactate dehydrogenase (EC 1.1.1.27)
Gene Symbol LDHC
Organism Homo sapiens (Human)
Length 318 aa
Isoforms No isoforms
Related PMIDs 31251020
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 1.000
24/46 (52.2%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSTVKEQLIE11KLIEDDENSQ21CKITIVGTGA31VGMACAISIL41LKDLADELAL
51-10051VDVALDKLKG61EMMDLQHGSL71FFSTSKITSG81KAGARQQEGE91TRLALVQRNV
101-150101AIMKSIIPAI111VHYSPDCKIL121VVSNPVDILT131YIVWKISGLP141VTRVIGSGCN
151-200151LDSARFRYLI161GEKLGVHPTS171CHGWIIGEHG181DSSVPLWSGV191NVAGVALKTL
201-250201DPKLGTDSDK211EHWKNIHKQV221IQSAYEIIKL231KGYTSWAIGL241SVMDLVGSIL
251-300251KNLRRVHPVS261TMVKGLYGIK271EELFLSIPCV281LGRNGVSDVV291KINLNSEEEA
301-318301LFKKSAETLW311NIQKDLIF
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
35 Prediction (Medium) - -
149 CYSMODDB SWISSPALM DBPTM Prediction (High) - -
279 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
106 R → C 0.002141 SNP Missense Mutation SKCM
112 R → C 0.001764 SNP Missense Mutation LUAD
112 R → C 0.001887 SNP Missense Mutation UCEC
157 R → C 0.001969 SNP Missense Mutation HNSC
157 R → C 0.004283 SNP Missense Mutation SKCM