Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F5H2L3 | DDB1 | Damage specific DNA binding protein … | Homo sapiens (Human) | 165 aa |
Protein Details: F5H2L3 (DDB1)
Protein Information
| Accession | F5H2L3 |
|---|---|
| Protein Names | Damage specific DNA binding protein 1 |
| Gene Symbol | DDB1 |
| Organism | Homo sapiens (Human) |
| Length | 165 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.857
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.857
24/46 (52.2%)
4
PC3 cells
Specificity: 0.143
4/4 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MYGKIAVMEL11FRPKGESKDL21LFILTAKYNA31CILEYKQSGE41SIDIITRAHG
51-10051NVQDRIGRPS61ETGIIGIIDP71ECRMIGLRLY81DGLFKVIPLD91RDNKELKAFN
101-150101IRLEELHVID111VKFLYGCQAP121TICFVYQDPQ131GRHVKTYEVS141LREKEFNKGP
151-165151WKQENVEAEA161SMVIA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 31 | Prediction (High) | - | - |
| 72 | CYSMODDB SWISSPALM DBPTM | RSE1/DDB1/CPSF1 first beta-propeller | - |
| 117 | Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 147 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 158 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 182 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 313 | C → C | 0.001887 | SNP | Silent | UCEC |
| 323 | F → C | 0.007299 | SNP | Missense Mutation | READ |
| 327 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 327 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 613 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 642 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 655 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 713 | R → C | 0.004283 | SNP | Missense Mutation | SKCM |
| 713 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 819 | C → C | 0.002141 | SNP | Silent | SKCM |
| 928 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 928 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 1047 | W → Cfs*15 | 0.002976 | INS | Frame Shift Ins | KIRC |