Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F5H6I7 | ATL3 | Atlastin GTPase 3 | Homo sapiens (Human) | 523 aa |
Protein Details: F5H6I7 (ATL3)
Protein Information
| Accession | F5H6I7 |
|---|---|
| Protein Names | Atlastin GTPase 3 |
| Gene Symbol | ATL3 |
| Organism | Homo sapiens (Human) |
| Length | 523 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 32944167 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MESSKPGPVQ11VVLVQKDQHS21FELDEKALAS31ILLQDHIRDL41DVVVVSVAGA
51-10051FRKGKSFILD61FMLRYLYSQK71ESGHSNWLGD81PEEPLTGFSW91RGGSDPETTG
101-150101IQIWSEVFTV111EKPGGKKVAV121VLMDTQGAFD131SQSTVKDCAT141IFALSTMTSS
151-200151VQIYNLSQNI161QEDDLQQLQL171FTEYGRLAMD181EIFQKPFQTL191MFLVRDWSFP
201-250201YEYSYGLQGG211MAFLDKRLQV221KEHQHEEIQN231VRNHIHSCFS241DVTCFLLPHP
251-300251GLQVATSPDF261DGKLKDIAGE271FKEQLQALIP281YVLNPSKLME291KEINGSKVTC
301-350301RGLLEYFKAY311IKIYQGEDLP321HPKSMLQATA331EANNLAAAAS341AKDIYYNNME
351-400351EVCGGEKPYL361SPDILEEKHC371EFKQLALDHF381KKTKKMGGKD391FSFRYQQELE
401-450401EEIKELYENF411CKHNGSKNVF421STFRTPAVLF431TGIVALYIAS441GLTGFIGLEV
451-500451VAQLFNCMVG461LLLIALLTWG471YIRYSGQYRE481LGGAIDFGAA491YVLEQASSHI
501-523501GNSTQATVRD511AVVGRPSMDK521KAQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 138 | - | - | - |
Deep-Palm: 0.37
|
|
| 238 | - | - | - |
Deep-Palm: 0.05
|
|
| 244 | - | - | - |
Deep-Palm: 0.21
|
|
| 300 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.74
Deep-Palm: 0.92
|
|
| 353 | - | - | - |
Deep-Palm: 0.46
|
|
| 370 | - | - | - |
Deep-Palm: 0.92
|
|
| 411 | - | - | - |
Deep-Palm: 0.41
|
|
| 457 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.89
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
PC3
Specificity: 0.500
3/3 (100.0%)
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
1
U937 cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 262 | C → C | 0.001887 | SNP | Silent | UCEC |
| 286 | A → Cfs*3 | 0.003559 | INS | Frame Shift Ins | KIRP |
| 489 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 497 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |