Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F5H8F7 | ASH2L | ASH2 like, histone lysine methyltransferase … | Homo sapiens (Human) | 489 aa |
Protein Details: F5H8F7 (ASH2L)
Protein Information
| Accession | F5H8F7 |
|---|---|
| Protein Names | ASH2 like, histone lysine methyltransferase complex subunit |
| Gene Symbol | ASH2L |
| Organism | Homo sapiens (Human) |
| Length | 489 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 31382980 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.917
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
11
LNCaP cells
Specificity: 0.917
11/46 (23.9%)
1
U937 cells
Specificity: 0.083
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTNYSFHCNV11CHHSGNTYFL21RKQANLKEMC31LSALANLTWQ41SRTQDEHPKT
51-10051MFSKDKDIIP61FIDKYWECMT71TRQRPGKMTW81PNNIVKTMSK91ERDVFLVKEH
101-150101PDPGSKDPEE111DYPKFGLLDQ121DLSNIGPAYD131NQKQSSAVST141SGNLNGGIAA
151-200151GSSGKGRGAK161RKQQDGGTTG171TTKKARSDPL181FSAQRLPPHG191YPLEHPFNKD
201-250201GYRYILAEPD211PHAPDPEKLE221LDCWAGKPIP231GDLYRACLYE241RVLLALHDRA
251-300251PQLKISDDRL261TVVGEKGYSM271VRASHGVRKG281AWYFEITVDE291MPPDTAARLG
301-350301WSQPLGNLQA311PLGYDKFSYS321WRSKKGTKFH331QSIGKHYSSG341YGQGDVLGFY
351-400351INLPEDTETA361KSLPDTYKDK371ALIKFKSYLY381FEEKDFVDKA391EKSLKQTPHS
401-450401EIIFYKNGVN411QGVAYKDIFE421GVYFPAISLY431KSCTVSINFG441PCFKYPPKDL
451-489451TYRPMSDMGW461GAVVEHTLAD471VLYHVETEVD481GRRSPPWEP
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 30 | Prediction (High) | - | - |
| 68 | Prediction (Medium) | - | - |
| 237 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 130 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 207 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 422 | Y → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 525 | F → Cfs*3 | 0.002288 | DEL | Frame Shift Del | STAD |
| 558 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |