Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F6UJC5 | DDX39B | DExD-box helicase 39B | Homo sapiens (Human) | 245 aa |
Protein Details: F6UJC5 (DDX39B)
Protein Information
| Accession | F6UJC5 |
|---|---|
| Protein Names | DExD-box helicase 39B |
| Gene Symbol | DDX39B |
| Organism | Homo sapiens (Human) |
| Length | 245 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MWTMSSWTMK11MMRWRQQLGE21MGLRPLPRRM31SRAPMSPSTA41LAFVTSCSSQ
51-10051SCSGPLSTVA61LSIRQKVAVF71FGGLSIKKDE81EVLKKNCPHI91VVGTPGRILA
101-150101LARNKSLNLK111HIKHFILDEC121DKMLEQLDMR131RDVQEIFRMT141PHEKQVMMFS
151-200151ATLSKEIRPV161CRKFMQDPME171IFVDDETKLT181LHGLQQYYVK191LKDNEKNRKL
201-245201FDLLDVLEFN211QVVIFVKSVQ221RCIALAQLLV231EQNFPAIAIH241RGMPQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 47 | - | - | - |
Deep-Palm: 0.95
|
|
| 52 | - | - | - |
Deep-Palm: 0.94
|
|
| 87 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.97
|
| 120 | - | - | - |
Deep-Palm: 0.84
|
|
| 161 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.27
|
| 222 | - | - |
LNCaP
(31251020)
Unknown
(32651440)
|
GPS-Palm: 0.89
Deep-Palm: 0.67
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.250
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 216 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 250 | F → C | 0.002545 | SNP | Missense Mutation | GBM |
| 296 | S → C | 0.002020 | SNP | Missense Mutation | PRAD |