Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VQ14 | CCT2 | T-complex protein 1 subunit beta … | Homo sapiens (Human) | 416 aa |
Protein Details: F8VQ14 (CCT2)
Protein Information
| Accession | F8VQ14 |
|---|---|
| Protein Names | T-complex protein 1 subunit beta (CCT-beta) |
| Gene Symbol | CCT2 |
| Organism | Homo sapiens (Human) |
| Length | 416 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.766
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.766
36/46 (78.3%)
4
Jurkat T cells
Specificity: 0.085
4/25 (16.0%)
4
PC3 cells
Specificity: 0.085
4/4 (100.0%)
3
Cerebral cortex
Specificity: 0.064
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MASLSLAPVN11IFKAGADEER21AETARLTSFI31GAIAIGDLVK41STLGPKGMDK
51-10051ILLSSGRDAS61LMVTNDGATI71LKNIGVDNPA81AKVLVDMSRV91QDDEVGDGTT
101-150101SVTVLAAELL111REAESLIAKK121IHPQTIIAGW131REATKAAREA141LLSSAVDHGS
151-200151DEVKFRQDLM161NIAGTTLSSK171LLTHHKDHFT181KLAVEAVLRL191KGSGNLEAIH
201-250201IIKKLGGSLA211DSYLDEGFLL221DKKIGVNQPK231RIENAKILIA241NTGMDTDKIK
251-300251IFGSRVRVDS261TAKVAEIEHA271EKEKMKEKVE281RILKHGINCF291INRQLIYNYP
301-350301EQLFGAAGVM311AIEHADFAGV321ERLALVTGGE331IASTFDHPEL341VKLGSCKLIE
351-400351EVMIGEDKLI361HFSGVALGEA371CTIVLRGATQ381QILDEAERSL391HDALCVLAQT
401-416401VKDSRTVYGG411VANHHS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 289 | Prediction (High) | - | - |
| 371 | Prediction (Medium) | - | - |
| 395 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | TCP-1/cpn60 chaperonin family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 371 | C → C | 0.001887 | SNP | Silent | UCEC |
| 438 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 456 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |