Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VQW8 | SLC38A2 | Sodium-coupled neutral amino acid symporter … | Homo sapiens (Human) | 344 aa |
Protein Details: F8VQW8 (SLC38A2)
Protein Information
| Accession | F8VQW8 |
|---|---|
| Protein Names | Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) |
| Gene Symbol | SLC38A2 |
| Organism | Homo sapiens (Human) |
| Length | 344 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.829
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
29
LNCaP cells
Specificity: 0.829
29/46 (63.0%)
4
PC3 cells
Specificity: 0.114
4/4 (100.0%)
2
DU145 cells
Specificity: 0.057
2/2 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSPVRRCVYF11SEDICDCFDL21VSVFFRLWYL31NGNYLVLLVS41LVVILPLSLF
51-10051RNLGYLGYTS61GLSLLCMVFF71LIVVICKKFQ81VPCPVEAALI91INETINTTLT
101-150101QPTALVPALS111HNVTENDSCR121PHYFIFNSQT131VYAVPILIFS141FVCHPAVLPI
151-200151YEELKDRSRR161RMMNVSKISF171FAMFLMYLLA181ALFGYLTFYE191HVESELLHTY
201-250201SSILGTDILL211LIVRLAVLMA221VTLTVPVVIF231PIRSSVTHLL241CASKDFSWWR
251-300251HSLITVSILA261FTNLLVIFVP271TIRDIFGFIG281ASAASMLIFI291LPSAFYIKLV
301-344301KKEPMKSVQK311IGALFFLLSG321VLVMTGSMAL331IVLDWVHNAP341GGGH
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 76 | Prediction (Medium) | - | - |
| 83 | Prediction (Medium) | - | - |
| 241 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 228 | C → F | 0.001969 | SNP | Missense Mutation | HNSC |
| 238 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 332 | F → Cfs*28 | 0.002506 | INS | Frame Shift Ins | COAD |
| 332 | F → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 342 | A → Cfs*14 | 0.002427 | INS | Frame Shift Ins | BLCA |
| 376 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 411 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |