Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| F8VQW8 | SLC38A2 | Sodium-coupled neutral amino acid symporter … | Homo sapiens (Human) | 344 aa |
Protein Details: F8VQW8 (SLC38A2)
Protein Information
| Accession | F8VQW8 |
|---|---|
| Protein Names | Sodium-coupled neutral amino acid symporter 2 (Amino acid transporter A2) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) |
| Gene Symbol | SLC38A2 |
| Organism | Homo sapiens (Human) |
| Length | 344 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSPVRRCVYF11SEDICDCFDL21VSVFFRLWYL31NGNYLVLLVS41LVVILPLSLF
51-10051RNLGYLGYTS61GLSLLCMVFF71LIVVICKKFQ81VPCPVEAALI91INETINTTLT
101-150101QPTALVPALS111HNVTENDSCR121PHYFIFNSQT131VYAVPILIFS141FVCHPAVLPI
151-200151YEELKDRSRR161RMMNVSKISF171FAMFLMYLLA181ALFGYLTFYE191HVESELLHTY
201-250201SSILGTDILL211LIVRLAVLMA221VTLTVPVVIF231PIRSSVTHLL241CASKDFSWWR
251-300251HSLITVSILA261FTNLLVIFVP271TIRDIFGFIG281ASAASMLIFI291LPSAFYIKLV
301-344301KKEPMKSVQK311IGALFFLLSG321VLVMTGSMAL331IVLDWVHNAP341GGGH
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 7 | - | - | - |
Deep-Palm: 0.02
|
|
| 15 | - | - | - |
Deep-Palm: 0.16
|
|
| 17 | - | - | - |
Deep-Palm: 0.17
|
|
| 66 | - | - | - |
Deep-Palm: 0.37
|
|
| 76 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.90
|
|
| 83 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.34
|
|
| 119 | - | - | - |
Deep-Palm: 0.23
|
|
| 143 | - | - | - |
Deep-Palm: 0.41
|
|
| 241 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.78
Deep-Palm: 0.79
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
LNCaP
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 228 | C → F | 0.001969 | SNP | Missense Mutation | HNSC |
| 238 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 332 | F → Cfs*28 | 0.002506 | INS | Frame Shift Ins | COAD |
| 332 | F → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 342 | A → Cfs*14 | 0.002427 | INS | Frame Shift Ins | BLCA |
| 376 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 411 | W → C | 0.002033 | SNP | Missense Mutation | LUSC |