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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
F8VQY6 RPLP0 Large ribosomal subunit protein uL10 … Homo sapiens (Human) 142 aa

Protein Details: F8VQY6 (RPLP0)

Protein Information
AccessionF8VQY6
Protein NamesLarge ribosomal subunit protein uL10 (60S acidic ribosomal protein P0)
Gene SymbolRPLP0
OrganismHomo sapiens (Human)
Length142 aa
IsoformsNo isoforms
Related PMIDs 31251020 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPREDRATWK11SNYFLKIIQL21LDDYPKCFIV31GADNVGSKQM41QQIRMSLRGK
51-10051AVVLMGKNTM61MRKAIRGHLE71NNPALEKLLP81HIRGNVGFVF91TKEDLTEIRD
101-142101MLLANKVPAA111ARAGAIAPCE121VTVPAQNTGL131GPEKTSFFQA141LE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
27 Large ribosomal subunit protein uL10 Universal ribosomal protein uL10 Large ribosomal subunit protein uL10-like domain superfamily - -
GPS-Palm: 0.79
Deep-Palm: 0.90
119 SWISSPALM DBPTM CYSMODDB Insertion domain in 60S ribosomal protein L10P -
cerebral cortex (36430497)
GPS-Palm: 0.91
Deep-Palm: 0.97
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 0.500
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.500
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
27 C → R 0.001887 SNP Missense Mutation UCEC
44 R → C 0.001887 SNP Missense Mutation UCEC
48 R → C 0.002033 SNP Missense Mutation LUSC
273 S → C 0.003460 SNP Missense Mutation CESC